Type | Description |
---|---|
Definition | Dicer-2 |
Date | Results | Publications |
---|---|---|
2019-07-20 12:52:00 | mutating Dicer-2 results in enhanced Zika virus load and increased susceptibility to Zika virus infection | 30305326 |
2018-07-07 12:09:00 | The results uncover a novel function of Dicer-2 in activation of mRNA translation through cytoplasmic polyadenylation. | 29317541 |
2018-06-09 12:20:00 | studies indicate that the 22 amino acids at the C terminus of Loqs-PD, including an FDF-like motif, directly interact with the Hel2 subdomain of Dicer-2's helicase domain. This interaction is RNA-independent, but we find that modulation of Dicer-2 cleavage also requires dsRNA binding by Loqs-PD. | 28874570 |
2018-05-05 10:58:00 | this study used cryo-electron microscopy to solve structures of Drosophila Dicer-2 alone and in complex with blunt dsRNA. | 29269422 |
2018-04-14 10:36:00 | Loqs-PD removes the inhibitory effect of inorganic phosphate on Dicer-2 processing of blunt-end hairpin RNAs, allowing siRNA production in the presence of inorganic phosphate. | 29550490 |
Type | IDs |
---|---|
Synonymous | CG6493, DCR-2, DCR2, DICER, Dcr, Dcr2, Dicer, Dicer2, Dmel\CG6493, cg6493, dDcr2, dcr, dcr-2, dcr2, dic2, dicer, dicer-2, dicer2, dmDcr-2 |
Gene |
UniProtKB-ID:
A1ZAW0_DROME,
A0A0B4LFK8_DROME
UniprotKB:
A1ZAW0,
A0A0B4LFK8
UniParc:
UPI00000749CE,
UPI0002B8CDA4
EMBL:
BT128787,
AE013599
EnsemblGenome:
FBgn0034246
KO:
dme:Dmel_CG6493
|
Nucleutide sequences |
EMBL-CDS:
AEL30809.1,
AAF57830.2,
AHN56336.1
Gene_ORFName:
CG6493,
Dmel_CG6493,
CG6493,
Dmel_CG6493
EnsemblGenome_TRS:
FBtr0086904,
FBtr0340217
|
Protein sequencees |
EnsemblGenome_PRO:
FBpp0086061,
FBpp0309192
RefSeq:
NP_523778.2,
NP_001286540.1
|
Others |
UniRef100:
UniRef100_A0A0B4LFK8,
UniRef100_A1ZAW0
UniRef90:
UniRef90_A1ZAW0
UniRef50:
UniRef50_A1ZAW0
UniGene:
Dm.7764
|