| Type | Description |
|---|---|
| Definition | Plenty of SH3s |
| Date | Results | Publications |
|---|---|---|
| 2019-02-09 12:55:00 | The pro-apoptotic JNK scaffold protein POSH mediates CHMP2BIntron5-associated toxicity in animal models of frontotemporal dementia. | 29432529 |
| 2018-08-04 12:16:00 | The findings establish POSH as a crucial regulator that integrates the signal from the cell surface to negatively regulate Ex-mediated Hippo activation in Drosophila. | 29440430 |
| 2015-06-20 11:28:00 | The data data uncover Rab8, POSH, and TAK1 as regulators of synaptic growth responses and point to recycling endosome as a key compartment for synaptic growth regulation during neurodegenerative processes. | 25800055 |
| 2011-04-23 10:47:00 | evidence that the JNK pathway scaffold protein, POSH, is involved in TNF (Eiger) signaling in Drosophila | 20933214 |
| 2011-01-01 10:42:00 | POSH promotes cell survival in Drosophila and in human rheumatoid arthritis synovial fibroblasts | 20974134 |
| Type | IDs |
|---|---|
| Synonymous | 155116_at, BEST:GM09451, CG4909, DPOSH, Dmel\CG4909, GM09451, dPOSH, l(2)k15815, posh |
| Gene |
UniProtKB-ID:
Q7K4D1_DROME
UniprotKB:
Q7K4D1
UniParc:
UPI00000775A7
EMBL:
AE013599,
AY051984
EnsemblGenome:
FBgn0040294
KO:
dme:Dmel_CG4909
|
| Nucleutide sequences |
EMBL-CDS:
AAF57833.1,
AAK93408.1
Gene_ORFName:
Dmel_CG4909,
CG4909
EnsemblGenome_TRS:
FBtr0086828
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0086007
RefSeq:
NP_523776.1
|
| Others |
UniRef100:
UniRef100_Q7K4D1
UniRef90:
UniRef90_Q7K4D1
UniRef50:
UniRef50_Q7K4D1
UniGene:
Dm.3323
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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