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3694 ITGB6

3694

ITGB6

integrin subunit beta 6

protein-coding

Homo sapiens

基因描述

Type Description
Definition integrin subunit beta 6

研究结论

Date Results Publications
2020-10-03 12:54:00 Integrin alphavbeta6 mediates epithelial-mesenchymal transition in human bronchial epithelial cells induced by lipopolysaccharides of Pseudomonas aeruginosa via TGF-beta1-Smad2/3 signaling pathway. 31243731
2020-09-12 12:39:00 These findings provide insights into the molecular mechanism underlying ITGB6 overexpression in oral squamous cell carcinomas and may have important implications for therapeutic purposes. 30998970
2020-04-18 11:21:00 Integrin alphavbeta6 promotes pancreatic ductal adenocarcinoma growth through both tumour cell and tumour microenvironment mechanisms. 31259422
2020-02-08 11:35:00 ITGB6 is present in the serum of colorectal carcinoma (CRC), but not in non-CRC control patients, predicted the onset of metastatic disease and was associated with poor prognosis. 30653264
2019-11-09 11:56:00 Oncolytic Ad5NULL-A20 virotherapies represent an excellent vector for local and systemic targeting of alpha5 beta 6-overexpressing cancers and exciting platforms for tumor-selective overexpression of therapeutic anticancer modalities, including immune checkpoint inhibitors. 29798908

名称对应

Type IDs
Synonymous AI1H
Gene
UniProtKB-ID: ITB6_HUMAN, B4E2B8_HUMAN, A0A087WXP3_HUMAN, E9PEE8_HUMAN
UniprotKB: P18564, B4E2B8, A0A087WXP3, E9PEE8
UniParc: UPI00017A8724, UPI0000F01D9E, UPI0003907455, UPI000012DA13, UPI0000E07B00
EMBL: AK304203, S49380, AC080166, CH471058, AC092153, M35198, AK313944, BC121178
Ensembl: ENSG00000115221
KO: hsa:3694
Nucleutide sequences
EMBL-CDS: AAA36122.2, EAX11390.1, AAB23690.1, AAI21179.1, AAY24053.1, AAX93093.1, BAG36662.1, BAG65080.1
Ensembl_TRS: ENST00000409967, ENST00000283249, ENST00000409872, ENST00000620391, ENST00000428609
Protein sequencees
Ensembl_PRO: ENSP00000386828, ENSP00000386367, ENSP00000283249, ENSP00000481183, ENSP00000408024
RefSeq: NP_001269282.1, NP_001269318.1, NP_001269283.1, NP_000879.2, NP_001269319.1, NP_001269284.1, NP_001269317.1
Others
UniRef100: UniRef100_P18564, UniRef100_E9PEE8, UniRef100_B4E2B8, UniRef100_A0A087WXP3
UniRef90: UniRef90_P18564, UniRef90_G3R1W1
UniRef50: UniRef50_P18564
UniGene: Hs.470399
CCDS: CCDS2212.1, CCDS63040.1

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