| Type | Description |
|---|---|
| Definition | A-Raf proto-oncogene, serine/threonine kinase |
| Date | Results | Publications |
|---|---|---|
| 2021-03-28 19:06:00 | Linc01232 promotes the metastasis of pancreatic cancer by suppressing the ubiquitin-mediated degradation of HNRNPA2B1 and activating the A-Raf-induced MAPK/ERK signaling pathway. | 32814086 |
| 2018-01-13 10:51:00 | The constitutive or induced re-localization of A-Raf to the plasma membrane compromises its ability to efficiently sequester and inactivate MST2, thus rendering cells susceptible to apoptosis | 26891695 |
| 2016-09-10 11:21:00 | This review discusses the regulation of A-Raf protein expression, and the roles of A-Raf in apoptosis and cancer, with a special focus on its role in resistance to Raf inhibitors. [review] | 26508523 |
| 2016-04-02 10:46:00 | analysis of FGFR2-PPHLN1 fusion and ARAF mutations in intrahepatic cholangiocarcinoma | 25608663 |
| 2015-04-25 10:25:00 | Aberrant expression of A-, B-, and C-RAF, and COT is frequent in PTC; increased expression of COT is correlated with recurrence of PTC. | 25674762 |
| Type | IDs |
|---|---|
| Synonymous | A-RAF, ARAF1, PKS2, RAFA1 |
| Gene |
UniProtKB-ID:
ARAF_HUMAN,
Q96II5_HUMAN,
A0A024R178_HUMAN
UniprotKB:
P10398,
Q96II5,
A0A024R178
UniParc:
UPI0000211F5C,
UPI000006F3DE,
UPI0000000C41
EMBL:
BC007514,
AL542736,
X04790,
CH471164,
KF459100,
Z84466,
U01337,
M13829,
BC002466,
L24038,
AB158254,
BT019864,
KU177914
Ensembl:
ENSG00000078061
KO:
hsa:369
|
| Nucleutide sequences |
EMBL-CDS:
AAH02466.1,
BAE66645.1,
AAA65219.1,
AAB03517.1,
AAB08754.1,
AAV38667.1,
CAA28476.1,
AAH07514.1,
EAW59312.1,
EAW59311.1,
ALQ33372.1
Gene_ORFName:
hCG_29140
Ensembl_TRS:
ENST00000377045,
ENST00000377039,
ENST00000290277
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000366244,
ENSP00000366238,
ENSP00000290277
RefSeq:
NP_001243125.1,
NP_001645.1,
NP_001243126.1
|
| Others |
UniRef100:
UniRef100_Q96II5,
UniRef100_P10398
UniRef90:
UniRef90_O19004,
UniRef90_P10398
UniRef50:
UniRef50_P10398,
UniRef50_O19004
UniGene:
Hs.446641
CCDS:
CCDS35232.1,
CCDS59164.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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