| Type | Description |
|---|---|
| Definition | integrin subunit alpha X |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:16:00 | Association of Electronegative LDL with Macrophage Foam Cell Formation and CD11c Expression in Rheumatoid Arthritis Patients. | 32824307 |
| 2021-04-17 13:12:00 | An Allosteric Shift in CD11c Affinity Activates a Proatherogenic State in Arrested Intermediate Monocytes. | 33055281 |
| 2020-02-29 11:04:00 | ITGAX stimulates angiogenesis of ovarian cancer through the PI3K/Akt signaling-mediated VEGF-A/VEGFR2 expression in endothelial cells, suggesting that ITGAX may be a novel target in the treatment of cancers, especially those with high angiogenic capacity. | 30873824 |
| 2019-12-28 11:44:00 | results suggested that ITGAX and ITGAM gene polymorphisms were associated with IgA nephropathy (IgAN) in a Chinese Han population, and the rs11150619-T allele showed a potential protective role for IgAN. | 31227791 |
| 2019-01-26 11:46:00 | We demonstrated a strong correlation of CD11c expression, which represents dendritic cells (DCs) , with Tumor-infiltrating lymphocytes (TILs) and TLSs in triple-negative breast cancer (TNBC). Further investigation is warranted to identify therapeutic modalities that facilitate recruitment and activation of DCs. | 30348717 |
| Type | IDs |
|---|---|
| Synonymous | CD11C, SLEB6 |
| Gene |
UniProtKB-ID:
ITAX_HUMAN,
H3BN02_HUMAN
UniprotKB:
P20702,
H3BN02
UniParc:
UPI00001C0366,
UPI000041E001
EMBL:
M29485,
AC093520,
BC038237,
M29487,
M81695,
M29165,
M29482,
M29486,
M29484,
M29483
Ensembl:
ENSG00000140678
KO:
hsa:3687
|
| Nucleutide sequences |
EMBL-CDS:
AAA59180.1,
AAA51620.1,
AAH38237.1
Ensembl_TRS:
ENST00000268296,
ENST00000562522
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000268296,
ENSP00000454623
RefSeq:
XP_024306031.1,
XP_011544156.1,
XP_011544154.1,
NP_000878.2,
NP_001273304.1
|
| Others |
UniRef100:
UniRef100_P20702,
UniRef100_H3BN02
UniRef90:
UniRef90_P20702
UniRef50:
UniRef50_P11215
UniGene:
Hs.248472
CCDS:
CCDS10711.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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