| Type | Description |
|---|---|
| Definition | pancreas associated transcription factor 1a |
| Date | Results | Publications |
|---|---|---|
| 2016-12-17 11:48:00 | Results highlight the possibility that Ptf1a may act as an important transcription factor for enteric neuron development. | 26865080 |
| 2016-02-20 11:16:00 | In ptf1a haploinsufficiency, more ptf1a-lineage-labeled cells are traced into the pancreatic Notch-responsive cell and endocrine compartments. More reduction of ptf1a gene dosage converts pancreatic progenitor cells to non-pancreatic cell fates. | 25773748 |
| 2013-11-16 11:51:00 | Autoregulation of ptf1a is absolutely required for exocrine pancreas formation. | 23876428 |
| 2011-08-27 10:50:00 | Postembryonic antagonism of Ptf1a, a master regulator of pancreatic development and acinar cell fate specification, induced expression of endocrine genes including insulin in the exocrine compartment. Induced insulin+ cells are derived from acinar cells. | 21497092 |
| 2010-01-21 13:14:00 | The timing of Ptf1a expression suggests that it is involved in the very early stages or steps in the differentiation of amacrine cells, which can be seen to rapidly diversify into a large number of subtypes. | 19732413 |
| Type | IDs |
|---|---|
| Synonymous | PTF1, si:zc142h2.2, zgc:112216 |
| Gene |
UniProtKB-ID:
PTF1A_DANRE
UniprotKB:
Q7ZSX3
UniParc:
UPI0000004442
EMBL:
BC093269,
AY245546,
AL845362
Ensembl:
ENSDARG00000014479
KO:
dre:368662
|
| Nucleutide sequences |
EMBL-CDS:
AAH93269.1,
CAD60845.1,
AAO92259.1
Gene_ORFName:
zgc:112216,
si:zc142h2.2
Ensembl_TRS:
ENSDART00000021987
|
| Protein sequencees |
Ensembl_PRO:
ENSDARP00000011265
RefSeq:
NP_997524.1
|
| Others |
UniRef100:
UniRef100_Q7ZSX3
UniRef90:
UniRef90_Q7ZSX3
UniRef50:
UniRef50_Q7ZSX3
UniGene:
Dr.86563
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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