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368476 pcdh15a

368476

pcdh15a

protocadherin-related 15a

protein-coding

Danio rerio

基因描述

Type Description
Definition protocadherin-related 15a

研究结论

Date Results Publications
2018-06-16 10:49:00 Itga8 and Pcdh15 act as a complex to regulate cilia biogenesis in sensory cells. 28883094
2017-08-19 11:47:00 links transmit force to mechanotransduction channels at the tip of hair bundles in sensory hair cells. One component of tip links is Protocadherin 15 (PCDH15). Here, we demonstrate that, when transgenically expressed, either zebrafish Pcdh15a-cytodomain 1 (CD1) or Pcdh15a-CD3 can rescue the phenotype of a pcdh15a-null mutant. 28219986
2014-11-22 10:57:00 These results identify an evolutionarily conserved association between the fish and mouse orthologs of PCDH15 and TMC1 and TMC2, supporting the notion that TMCs are key components of the transduction complex in hair cells. 25114259
2010-01-21 00:00:00 after a duplication of pcdh15, one gene retained an essential function in the ear and the other in the eye 15634702

名称对应

Type IDs
Synonymous PCDH15, si:bac7cse.1, si:xx-bac7cse.1
Gene
UniProtKB-ID: Q5ICW6_DANRE, A0A1V0D7A1_DANRE
UniprotKB: Q5ICW6, A0A1V0D7A1
UniParc: UPI0007EEBDE6, UPI00004B51CA
EMBL: BX005204, CU075715, AY772390, CU467855, CU856144, CU467884, KY432405, BX324172, BX548002
Ensembl: ENSDARG00000098257
KO: dre:368476
Nucleutide sequences
EMBL-CDS: AAW50923.1, ARA90564.1
Ensembl_TRS: ENSDART00000164732, ENSDART00000163331, ENSDART00000188322
Protein sequencees
Ensembl_PRO: ENSDARP00000135210, ENSDARP00000130788, ENSDARP00000149410
RefSeq: XP_017214201.1, XP_009305800.1, XP_017214202.1, NP_001012500.1, XP_017214198.1, XP_017214200.1, XP_017214203.1, XP_009305802.1, XP_017214199.1
Others
UniRef100: UniRef100_A0A1V0D7A1, UniRef100_Q5ICW6
UniRef90: UniRef90_Q5ICW6, UniRef90_A0A1V0D7A1
UniRef50: UniRef50_Q99PJ1-11, UniRef50_Q5ICW6
UniGene: Dr.61053

全选

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研究热度

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