| Type | Description |
|---|---|
| Definition | integrin subunit alpha L |
| Date | Results | Publications |
|---|---|---|
| 2021-02-06 13:51:00 | CD64, CD11a and CD18 leukocytes expression in children with SARS-CoV-2 multisystem inflammatory syndrome versus children with Kawasaki disease: Similar but not the same. | 33160625 |
| 2020-05-16 12:40:00 | Aggregatibacter actinomycetemcomitans LtxA has a strong affinity for the cytosolic domains of both the alphaL and beta2 subunits (Kd = 15 and 4.2 nM, respectively) of human LFA-1 and a significantly lower affinity for the cytoplasmic domains of other integrin alphaM , alphaX , and beta3 subunits (Kd = 400, 180, and 230 nM, respectively), used as controls. | 30329215 |
| 2019-09-21 10:41:00 | The down-regulation of hsa_circ_0012919, the sponge for miR-125a-3p, contributes to DNA methylation of CD11a and CD70 in CD4(+) T cells of systemic lupus erythematous | 30237316 |
| 2018-12-22 11:54:00 | LFA-1 cross-linking recruits and activates FAK1 and PYK2 to phosphorylate LAT selectively on a single Y-171 site that binds to the GRB2-SKAP1 complex and limits dwell times of T-cells with dendritic cells | 28699640 |
| 2018-10-20 11:59:00 | Data show that integrin alphaLbeta2 (LFA-1) is oriented relative to actin retrograde flow. | 29229906 |
| Type | IDs |
|---|---|
| Synonymous | CD11A, LFA-1, LFA1A |
| Gene |
UniProtKB-ID:
ITAL_HUMAN,
B2RAL6_HUMAN
UniprotKB:
P20701,
B2RAL6
UniParc:
UPI000013C4FF,
UPI000175076A,
UPI0000072F58,
UPI0000688144
EMBL:
AC002310,
AC116348,
DQ131904,
Y00796,
AK314246,
M95609,
Z22804,
M87662,
BC008777,
CH471192
Ensembl:
ENSG00000005844
KO:
hsa:3683
|
| Nucleutide sequences |
EMBL-CDS:
AAA16474.2,
AAZ38713.1,
AAC31672.1,
EAW52243.1,
AAH08777.1,
CAA80461.1,
CAA68747.1,
BAG36913.1
Ensembl_TRS:
ENST00000358164,
ENST00000356798
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000349252,
ENSP00000350886
RefSeq:
NP_002200.2,
XP_005255370.1,
NP_001107852.1,
XP_011544151.1,
XP_006721107.1,
XP_024306030.1
|
| Others |
UniRef100:
UniRef100_P20701,
UniRef100_B2RAL6
UniRef90:
UniRef90_P20701
UniRef50:
UniRef50_P20701
UniGene:
Hs.174103
CCDS:
CCDS45461.1,
CCDS32433.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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