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36793 clu

36793

clu

clueless

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition clueless

研究结论

Date Results Publications
2020-10-24 13:59:00 Clueless forms dynamic, insulin-responsive bliss particles sensitive to stress. 31837288
2017-07-29 11:25:00 Clu is upstream of and binds to VCP in vivo and promotes VCP-dependent Marf degradation in vitro Marf accumulates in whole muscle lysates of clu-deficient flies and is destabilized upon Clu overexpression. Thus, Clu is essential for mitochondrial homeostasis and functions in concert with Parkin and VCP for Marf degradation to promote damaged mitochondrial clearance. 26931463
2016-03-05 11:49:00 Clu directly modulates mitochondrial function, and that Clu's function contributes to the PINK1-Park pathway of mitochondrial quality control. 26035866
2013-11-16 11:12:00 Clueless (clu) is a novel regulator of activity. 23835532
2013-08-03 11:35:00 The results suggest Clu functions upstream of electron transport and oxidative phosphorylation, has a role in suppressing oxidative damage in the cell, and that lack of Clu's specific function causes mitochondria to mislocalize. 23342118

名称对应

Type IDs
Synonymous CG8443, Clu, Dmel\CG8443, anon-WO0118547.143
Gene
UniProtKB-ID: CLU_DROME, A0A0B4KEX0_DROME
UniprotKB: A1ZAB5, A0A0B4KEX0
UniParc: UPI000008198F, UPI0002942821
EMBL: BT011344, AE013599
EnsemblGenome: FBgn0034087
KO: dme:Dmel_CG8443
Nucleutide sequences
EMBL-CDS: AAR96136.1, AAF58047.1, AGB93553.1
Gene_ORFName: CG8443, CG8443, Dmel_CG8443
EnsemblGenome_TRS: FBtr0087242, FBtr0333169
Protein sequencees
EnsemblGenome_PRO: FBpp0086380, FBpp0305372
RefSeq: NP_611095.1, NP_001261021.1
Others
UniRef100: UniRef100_A1ZAB5
UniRef90: UniRef90_A1ZAB5
UniRef50: UniRef50_A1ZAB5
UniGene: Dm.7233

全选

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研究热度

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