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36791 Lis-1

36791

Lis-1

Lissencephaly-1

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition Lissencephaly-1

研究结论

Date Results Publications
2016-10-08 10:10:00 lowering levels of Lissencephaly-1 (Lis1), a dynein motor co-factor, augments axonal mitochondrial transport in ageing wing neurons. 26598558
2013-11-30 12:36:00 The data reveal a critical role for Lis1 within the mRNA localization machinery and suggest a model in which Lis1 facilitates motor complex association with cargos by promoting the interaction of dynein with dynactin. 23918939
2013-01-12 10:02:00 A general role of Lis-1/NudE, Dynein and microtubules, in cell-on-cell migration, is reported. 22808215
2012-10-20 10:20:00 present a model in which Lis-1 and asun cooperate to regulate dynein localization and centrosome positioning during spermatogenesis 22764052
2011-01-01 11:34:00 Lis1, which is widely expressed in adult mammalian tissues, could regulate adult tissue stem cells through modulating niche signaling and adhesion. 21041636

名称对应

Type IDs
Synonymous CG8440, D-Lis1, DLIS-1, DLIS1, DLis-1, DLis1, Dlis-1, Dlis1, DmLIS1, Dmel\CG8440, LIS-1, Lis 1, Lis1, dLis1, l(2)k13209, l(2R)W8, lis-1, lis1, n(2)k11702
Gene
UniProtKB-ID: LIS1_DROME, A0A0B4K812_DROME
UniprotKB: Q7KNS3, A0A0B4K812
UniParc: UPI000007BE62
EMBL: AY089600, AF152419, AF098070, BT021404, AF117606, AE013599
EnsemblGenome: FBgn0015754
KO: dme:Dmel_CG8440
Nucleutide sequences
EMBL-CDS: AAD13113.1, AAC83821.1, AAS64845.1, AAO41380.1, AAX33552.1, AAD38390.1, AAF58050.1, AAL90338.1, AFH08114.1
Gene_ORFName: CG8440, Dmel_CG8440, CG8440
EnsemblGenome_TRS: FBtr0087236, FBtr0087241, FBtr0304747, FBtr0087240, FBtr0087240, FBtr0087236, FBtr0304747, FBtr0087241
Protein sequencees
EnsemblGenome_PRO: FBpp0089100, FBpp0086375, FBpp0086379, FBpp0293289, FBpp0293289, FBpp0089100, FBpp0086379, FBpp0086375
RefSeq: NP_995852.1, NP_788370.1, NP_001246361.1, NP_477160.1
Others
UniRef100: UniRef100_Q7KNS3
UniRef90: UniRef90_Q7KNS3
UniRef50: UniRef50_Q7KNS3
UniGene: Dm.646

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