| Type | Description |
|---|---|
| Definition | Myelodysplasia/myeloid leukemia factor |
| Date | Results | Publications |
|---|---|---|
| 2017-08-19 11:36:00 | our data indicate that the MLF/DnaJ-1-dependent increase in Lz level allows the repression of Notch expression and signaling to prevent aberrant blood cell development. Thus our findings establish a functional link between MLF and the co-chaperone DnaJ-1 to control RUNX transcription factor activity and Notch signaling during blood cell development in vivo. | 28742844 |
| 2012-05-26 11:30:00 | mlf participates in a positive feedback loop to fine tune the activity of the RUNX transcription factor Lozenge (LZ) during development of the crystal cells. | 22411814 |
| 2010-01-21 00:00:00 | role in the control of cell growth in eye development | 12408803 |
| 2010-01-21 00:00:00 | MLF1 has been described as mainly cytoplasmic, but in Drosophila, one of the dMLF isoforms (dMLFA) localized mainly in the nucleus. | 18159124 |
| 2010-01-21 00:00:00 | Mlf and its mutant were characterized. Mlf can act developmentaly and post-developmentally to suppress neurodegeneration and premature aging in a cerebellar ataxia model. | 17121541 |
| Type | IDs |
|---|---|
| Synonymous | BcDNA:SD18148, CG8295, Dmel\CG8295, MLF, dMLF, dmlf, mlf |
| Gene |
UniProtKB-ID:
MLF_DROME,
E1JH79_DROME,
A0A0B4K7R5_DROME,
A0A0B4K807_DROME
UniprotKB:
Q9NKV0,
E1JH79,
A0A0B4K7R5,
A0A0B4K807
UniParc:
UPI000007FB11,
UPI000000148A,
UPI000034E067,
UPI00003FB2D9,
UPI000237F4F7,
UPI0000007715,
UPI00001E0D29
EMBL:
AY118583,
BT001895,
AY037049,
AE013599,
AB043986
EnsemblGenome:
FBgn0034051
KO:
dme:Dmel_CG8295
|
| Nucleutide sequences |
EMBL-CDS:
AAM70969.1,
AAS64849.1,
AAK63191.1,
BAA96391.1,
AAM49952.1,
AAN71684.1,
AAF58093.2,
AAM70968.2,
AFH08109.1,
ACZ94436.1,
AFH08107.1,
AFH08108.1
Gene_ORFName:
CG8295,
Dmel_CG8295,
CG8295,
Dmel_CG8295,
CG8295,
CG8295,
Dmel_CG8295
EnsemblGenome_TRS:
FBtr0087292,
FBtr0087293,
FBtr0087294,
FBtr0087295,
FBtr0306651,
FBtr0302149,
FBtr0306649,
FBtr0306650
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0086428,
FBpp0086430,
FBpp0089346,
FBpp0086429,
FBpp0291359,
FBpp0297606,
FBpp0297604,
FBpp0297605
RefSeq:
NP_001163164.1,
NP_725501.2,
NP_995847.1,
NP_001246353.1,
NP_001246354.1,
NP_725502.1,
NP_523753.1,
NP_001246355.1
|
| Others |
UniRef100:
UniRef100_A0A0B4K7R5,
UniRef100_A0A0B4K807,
UniRef100_Q9NKV0,
UniRef100_E1JH79
UniRef90:
UniRef90_Q9NKV0-2,
UniRef90_Q9NKV0
UniRef50:
UniRef50_Q9NKV0,
UniRef50_Q9NKV0-2
UniGene:
Dm.12915
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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