| Type | Description |
|---|---|
| Definition | integrin subunit alpha 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-13 13:26:00 | Overexpressed ITGA2 contributes to paclitaxel resistance by ovarian cancer cells through the activation of the AKT/FoxO1 pathway. | 32202508 |
| 2021-02-13 13:23:00 | L-Selectin P213S and Integrin Alpha 2 C807T Genetic Polymorphisms in Pediatric Sickle Cell Disease Patients. | 32433445 |
| 2020-08-12 11:34:00 | The study unravels the interplay between integrin-alpha2beta1/-alpha5beta1 and EGFR in anoikis resistance and suggest that the resistant cells are cancer initiating or cancer stem cells, which may serve as a promising target to combat metastasis of cancer. | 31641961 |
| 2020-06-06 11:05:00 | bone marrow-derived mesenchymal stem cells -derived exosomes overexpressing miR-16-5p restricted the progression of colorectal cancer by downregulating ITGA2 | 31102273 |
| 2020-05-23 11:38:00 | we show that gene expression profiling of RUNX1 knock-down or mutated MK provides a suitable approach to identify novel RUNX1 targets, among which downregulation of TREML1 and ITGA2 clearly contribute to the platelet phenotype of familial platelet disorder with predisposition to AML. | 30545930 |
| Type | IDs |
|---|---|
| Synonymous | BR, CD49B, GPIa, HPA-5, VLA-2, VLAA2 |
| Gene |
UniProtKB-ID:
ITA2_HUMAN
UniprotKB:
P17301
UniParc:
UPI000012D9ED
EMBL:
X17033,
L24121,
AF512556
Ensembl:
ENSG00000164171
KO:
hsa:3673
|
| Nucleutide sequences |
EMBL-CDS:
AAA16619.2,
CAA34894.1,
AAM34795.1
Ensembl_TRS:
ENST00000296585
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000296585
RefSeq:
NP_002194.2
|
| Others |
UniRef100:
UniRef100_P17301
UniRef90:
UniRef90_P17301
UniRef50:
UniRef50_P17301
UniGene:
Hs.482077
CCDS:
CCDS3957.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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