| Type | Description |
|---|---|
| Definition | ISL LIM homeobox 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-13 13:20:00 | microRNA-9 and -29a regulate the progression of diabetic peripheral neuropathy via ISL1-mediated sonic hedgehog signaling pathway. | 32544883 |
| 2020-12-19 13:43:00 | Generation and optimization of highly pure motor neurons from human induced pluripotent stem cells via lentiviral delivery of transcription factors. | 32783653 |
| 2020-11-21 13:35:00 | [Discovery and functional analysis of a novel ISL1 variant associated with congenital heart defect]. | 32820510 |
| 2020-09-12 13:11:00 | The Isl1 binds to compacted chromatin and works in concert with the Brg1-Baf60c-based SWI/SNF complex to promote permissive cardiac lineage-specific alterations in the chromatin landscape not only of genes with critical functions in cardiac progenitor cells, but also of cardiomyocyte structural genes that are highly expressed when Isl1 itself is no longer present. | 31024170 |
| 2020-05-23 10:04:00 | Heterozygous ISL1 nonsense mutation contributes to the pathogenesis of dilated cardiomyopathy. | 30536204 |
| Type | IDs |
|---|---|
| Synonymous | ISLET1, Isl-1 |
| Gene |
UniProtKB-ID:
ISL1_HUMAN
UniprotKB:
P61371
UniParc:
UPI0000023E3A
EMBL:
BC031213,
S70721,
U07559
Ensembl:
ENSG00000016082
KO:
hsa:3670
|
| Nucleutide sequences |
EMBL-CDS:
AAD14064.1,
AAH31213.1,
AAA81946.1
Ensembl_TRS:
ENST00000230658
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000230658
RefSeq:
XP_011541682.1,
NP_002193.2
|
| Others |
UniRef100:
UniRef100_P61371
UniRef90:
UniRef90_P61371
UniRef50:
UniRef50_P61371
UniGene:
Hs.505
CCDS:
CCDS43314.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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