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3669 ISG20

3669

ISG20

interferon stimulated exonuclease gene 20

protein-coding

Homo sapiens

基因描述

Type Description
Definition interferon stimulated exonuclease gene 20

研究结论

Date Results Publications
2018-12-01 10:09:00 we have identified a novel mechanism involving ISG20 induction by T3 via the signaling pathway to promote tumor angiogenesis in HCC. 29195126
2018-08-18 10:03:00 In conclusion, the authors identified that the influenza A virus-upregulated Long noncoding RNA lnc-ISG20 is a novel interferon-stimulated gene that elicits its inhibitory effect on influenza A virus replication by enhancing ISG20 expression. They demonstrated that lnc-ISG20 functions as a competitive endogenous RNA to bind miR-326 to reduce its inhibition of ISG20 translation. 29899085
2018-02-24 11:06:00 Interferon-stimulated gene of 20 kDa protein (ISG20) acts as an innate anti-HBV effector that selectively degrades hepatitis B virus (HBV) RNA and blocks replication of infectious HBV particles. 27626689
2017-09-23 14:08:00 Variation at rs12913965 may affect the risk for shoulder dislocation by affecting the activity of either TICRR or ISG20. 28521375
2017-05-13 21:58:00 We discovered two genome-wide significant SNPs. The first was novel and near ISG20. The second was in TRIOBP, a gene previously associated with prelingual nonsyndromic hearing loss. Motivated by our TRIOBP results, we also looked at exons in known hearing loss genes, and identified two additional SNPs, rs2877561 in ILDR1 and rs9493672 in EYA4 (at a significance threshold adjusted for number of SNPs in those regions). 27764096

名称对应

Type IDs
Synonymous CD25, HEM45
Gene
UniProtKB-ID: ISG20_HUMAN
UniprotKB: Q96AZ6
UniParc: UPI000049E313, UPI000006FE4D
EMBL: BT006952, BC007922, X89773, BC016341, CR456942, U88964
Ensembl: ENSG00000172183
KO: hsa:3669
Nucleutide sequences
EMBL-CDS: AAH16341.1, AAH07922.1, CAA61915.2, AAP35598.1, CAG33223.1, AAB53416.1
Ensembl_TRS: ENST00000560741, ENST00000306072
Protein sequencees
Ensembl_PRO: ENSP00000453638, ENSP00000306565
RefSeq: XP_016877636.1, NP_002192.2, XP_006720551.1, NP_001290163.1, NP_001290166.1, NP_001290162.1, XP_016877637.1, XP_011519823.1, XP_005254956.1, NP_001290165.1, NP_001290164.1
Others
UniRef100: UniRef100_Q96AZ6
UniRef90: UniRef90_Q96AZ6
UniRef50: UniRef50_Q96AZ6
UniGene: Hs.459265
CCDS: CCDS10345.1

全选

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