| Type | Description |
|---|---|
| Definition | insulin receptor substrate 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:17:00 | FGFR1 overexpression renders breast cancer cells resistant to metformin through activation of IRS1/ERK signaling. | 33007330 |
| 2021-03-20 13:30:00 | The long non-coding RNA DDX11-AS1 facilitates cell progression and oxaliplatin resistance via regulating miR-326/IRS1 axis in gastric cancer. | 32271422 |
| 2021-03-13 13:17:00 | MicroRNA-628-5p inhibits invasion and migration of human pancreatic ductal adenocarcinoma via suppression of the AKT/NF-kappa B pathway. | 31957029 |
| 2021-02-06 13:58:00 | Pyrosequencing analysis of IRS1 methylation levels in schizophrenia with tardive dyskinesia. | 32319643 |
| 2021-02-06 13:50:00 | Insulin receptor substrate 1 overexpression promotes survival of glioblastoma cells through AKT1 activation. | 32337956 |
| Type | IDs |
|---|---|
| Synonymous | HIRS-1 |
| Gene |
UniProtKB-ID:
IRS1_HUMAN
UniprotKB:
P35568
UniParc:
UPI000003BB52
EMBL:
S85963,
BC053895,
S62539
Ensembl:
ENSG00000169047
KO:
hsa:3667
|
| Nucleutide sequences |
EMBL-CDS:
AAB27175.1,
AAB21608.1,
AAH53895.1
Ensembl_TRS:
ENST00000305123
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000304895
RefSeq:
NP_005535.1
|
| Others |
UniRef100:
UniRef100_P35568
UniRef90:
UniRef90_P35568
UniRef50:
UniRef50_P35568
UniGene:
Hs.471508
CCDS:
CCDS2463.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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