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36645 BEAF-32

36645

BEAF-32

Boundary element-associated factor of 32kD

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition Boundary element-associated factor of 32kD

研究结论

Date Results Publications
2021-04-03 13:30:00 Promoter-Proximal Chromatin Domain Insulator Protein BEAF Mediates Local and Long-Range Communication with a and Directly Activates a Housekeeping Promoter in Drosophila. 32179582
2019-09-21 12:35:00 study shows that by virtue of O-GlcNAcylation, BEAF 32 is linked to epigenetic mechanisms that activate a subset of associated genes 28910574
2017-09-09 14:07:00 Loss of BEAF-32 does not noticeably impair the functions of the Hippo pathway in eye growth regulation. 27226322
2017-08-05 11:54:00 The BESS domain alone is sufficient to mediate BEAF-BEAF interactions, although the presence of the putative leucine zipper on at least one protein strengthens the interactions. BEAF-32B is sufficient to rescue a null BEAF mutation. Using mutant BEAF-32B rescue transgenes, we show that the middle region and the BESS domain are essential. 27622635
2017-03-25 11:41:00 we identify key roles for the Zelda and Zerknullt transcription factors in establishing the resulting expression domain, and find widespread binding of insulator proteins to the Mad and Brinker-bound genomic regions. Analysis of embryos lacking the BEAF-32 insulator protein shows reduced transcription of a peak BMP target gene and a reduction in the number of amnioserosa cells, the fate specified by peak BMP signaling. 27379389

名称对应

Type IDs
Synonymous BEAF, BEAF-32A, BEAF-32B, BEAF32, BEAF32A, BEAF32B, BEAF32b, Beaf-32, Beaf32, CG10159, Dmel\CG10159, beaf, bs04c01.y1
Gene
UniProtKB-ID: Q7JN06_DROME, Q94513_DROME
UniprotKB: Q7JN06, Q94513
UniParc: UPI0000082EA3, UPI00000776F0
EMBL: AE013599, X86007, Y09475, AY058711
EnsemblGenome: FBgn0015602
KO: dme:Dmel_CG10159
Nucleutide sequences
EMBL-CDS: CAA59994.1, AAF58205.1, CAA70621.1, AAG22264.1, AAL13940.1, AFH08082.1
Gene_ORFName: CG10159, Dmel_CG10159, CG10159, Dmel_CG10159
EnsemblGenome_TRS: FBtr0087441, FBtr0305588, FBtr0087442
Protein sequencees
EnsemblGenome_PRO: FBpp0086571, FBpp0086572, FBpp0294039
RefSeq: NP_523747.1, NP_725418.1, NP_001246328.1
Others
UniRef100: UniRef100_Q94513, UniRef100_Q7JN06
UniRef90: UniRef90_Q7JN06, UniRef90_Q94513
UniRef50: UniRef50_Q7JN06
UniGene: Dm.9114

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