| Type | Description |
|---|---|
| Definition | interferon regulatory factor 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:30:00 | ELF1 activated long non-coding RNA CASC2 inhibits cisplatin resistance of non-small cell lung cancer via the miR-18a/IRF-2 signaling pathway. | 32271431 |
| 2020-08-22 15:26:00 | Interferon regulatory factor 1 (IRF-1) and IRF-2 regulate PD-L1 expression in hepatocellular carcinoma (HCC) cells. | 32377817 |
| 2020-07-25 12:52:00 | Results identified IRF2 as a target of miR-18a. Furthermore, H19 regulated IRF2 expression level through miR-18a. | 30536700 |
| 2020-07-18 12:23:00 | IRF-2 was involved in regulating the invasion and migration of gastric cancer cells and negatively regulates the expression of MMP-1. | 31350707 |
| 2020-05-23 11:01:00 | IRF2 is a repressor of PD-L1. Thus, by downregulating a single nonessential gene, tumors become harder to see (reduced Ag presentation), more inhibitory (increased checkpoint inhibitor), and less susceptible to being killed by CD8(+) T cells. | 31471524 |
| Type | IDs |
|---|---|
| Synonymous | IRF-2 |
| Gene |
UniProtKB-ID:
IRF2_HUMAN
UniprotKB:
P14316
UniParc:
UPI0002656E3D,
UPI000012D888
EMBL:
AC099343,
CR457077,
CH471056,
X15949,
BC015803,
AK312953,
BT007264
Ensembl:
ENSG00000168310
KO:
hsa:3660
|
| Nucleutide sequences |
EMBL-CDS:
CAG33358.1,
EAX04677.1,
EAX04680.1,
EAX04678.1,
CAA34073.1,
AAP35928.1,
BAG35793.1,
AAH15803.1
Ensembl_TRS:
ENST00000393593
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000377218
RefSeq:
XP_024309806.1,
XP_024309803.1,
XP_024309802.1,
XP_024309804.1,
XP_024309805.1,
NP_002190.2,
XP_024309807.1
|
| Others |
UniRef100:
UniRef100_P14316
UniRef90:
UniRef90_P14316
UniRef50:
UniRef50_P14316
UniGene:
Hs.654566
CCDS:
CCDS3835.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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