| Type | Description |
|---|---|
| Definition | Optic atrophy 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-12-21 12:02:00 | The authors propose that Osa and its target genes opa and D form an incoherent feedforward loop (FFL) and a new mechanism allowing the successive expression of temporal identities in intermediate neural progenitors. | 31329099 |
| 2019-07-13 11:52:00 | Depletion of Mitofusin (dMfn) or Opa1 led to dysfunctional mitochondria, activation of Target of rapamycin (TOR) and a marked accumulation of lipid droplets. Enhancement of lipid utilization by the mitochondria attenuated TOR activation and rescued the loss of GSCs that was caused by inhibition of mitochondrial fusion. | 31160709 |
| 2017-05-27 11:07:00 | lack of ChChd3 leads to inactivation of Hippo activity under normal development, which is also dependent on the transcriptional coactivator Yorkie (Yki). Furthermore, loss of ChChd3 induces oxidative stress and activates the JNK pathway. In addition, depletion of other mitochondrial fusion components, Opa1 or Marf, inactivates the Hippo pathway as well. | 27317679 |
| 2014-08-23 10:47:00 | Mitochondrial fusion is regulated spatiotemporally by Ewg through Opa1-like during indirect flight muscles differentiation and growth. | 24198395 |
| 2011-12-24 10:04:00 | these results suggest that rho-7 and Opa1-like function in a common molecular pathway affecting mitochondrial function and apoptosis in Drosophila melanogaster. | 21945938 |
| Type | IDs |
|---|---|
| Synonymous | CG8479, Dmel\CG8479, OPA1, OPA1-like, Opa1-like, dOPA1, dOpa1, l(2)s3475, opa1, opa1-like |
| Gene |
UniProtKB-ID:
Q95U20_DROME,
A0A0B4LFB8_DROME,
A0A0B4LF33_DROME,
A0A0B4LGF5_DROME,
A1Z9N0_DROME
UniprotKB:
Q95U20,
A0A0B4LFB8,
A0A0B4LF33,
A0A0B4LGF5,
A1Z9N0
UniParc:
UPI00001E0C9C,
UPI00001E0C9D,
UPI0000078EB1,
UPI0002B8CDB3,
UPI0000078218
EMBL:
AY058366,
AE013599
EnsemblGenome:
FBgn0261276
KO:
dme:Dmel_CG8479
|
| Nucleutide sequences |
EMBL-CDS:
AAM70993.1,
AAL13595.1,
AHN56210.1,
AHN56211.1,
AHN56209.1,
AAF58275.2
Gene_ORFName:
CG8479,
Dmel_CG8479,
CG8479,
Dmel_CG8479,
Dmel_CG8479,
CG8479,
CG8479,
Dmel_CG8479,
Dmel_CG8479,
CG8479
EnsemblGenome_TRS:
FBtr0087573,
FBtr0339760,
FBtr0339761,
FBtr0339759,
FBtr0087574
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0086699,
FBpp0308807,
FBpp0308808,
FBpp0308806,
FBpp0086700
RefSeq:
NP_001286411.1,
NP_725369.1,
NP_610941.1,
NP_001286412.1,
NP_001286413.1
|
| Others |
UniRef100:
UniRef100_A0A0B4LF33,
UniRef100_A0A0B4LGF5,
UniRef100_A1Z9N0,
UniRef100_Q95U20,
UniRef100_A0A0B4LFB8
UniRef90:
UniRef90_A1Z9N0,
UniRef90_A0A0B4LF33,
UniRef90_Q95U20
UniRef50:
UniRef50_A0A0B4LF33,
UniRef50_Q5U3A7,
UniRef50_O60313-13
UniGene:
Dm.7707
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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