| Type | Description |
|---|---|
| Definition | O-fucosyltransferase 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-09-19 16:25:00 | Glycosylation of Specific Notch EGF Repeats by O-Fut1 and Fringe Regulates Notch Signaling in Drosophila. | 31722217 |
| 2011-01-08 10:51:00 | It regulates notch signaling by glycosylation.(review) | 21089381 |
| 2010-01-21 00:00:00 | For Notch signaling in Drosophila, the chaperone activity of OFUT1 is sufficient for the generation of functional Notch. | 18194540 |
| 2010-01-21 00:00:00 | O-fut1 is an extracellular component that is essential for the constitutive endocytic trafficking of Notch in Drosophila. | 17329366 |
| 2010-01-21 00:00:00 | Down-regulation of OFUT1 by RNA interference in Notch-secreting cells inhibits both Delta-Notch and Serrate-Notch binding, demonstrating a requirement for O-linked fucose for efficient binding of Notch to its ligands | 12909620 |
| Type | IDs |
|---|---|
| Synonymous | 4R6, AAF58290.1, CG12366, Dmel\CG12366, O-FUT1, O-fut, OFUT-1, OFUT1, OFut1, Ofut-1, Ofut1, l(2)SH2 2260, l(2)SH2260, ntc, nti, o-fut1 |
| Gene |
UniProtKB-ID:
OFUT1_DROME,
A8E6L6_DROME
UniprotKB:
Q9V6X7,
A8E6L6
UniParc:
UPI0000124629
EMBL:
AE013599,
BT030808,
AY118651,
AB093572,
BT021295
EnsemblGenome:
FBgn0033901
KO:
dme:Dmel_CG12366
|
| Nucleutide sequences |
EMBL-CDS:
AAM50020.1,
BAC55010.1,
AAF58290.1,
AAX33443.1,
ABV82190.1,
AHN56204.1
Gene_ORFName:
CG12366,
Dmel_CG12366,
CG12366
EnsemblGenome_TRS:
FBtr0087520,
FBtr0339959,
FBtr0087520,
FBtr0339959
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0086649,
FBpp0308981,
FBpp0308981,
FBpp0086649
RefSeq:
NP_610931.1,
NP_001286406.1
|
| Others |
UniRef100:
UniRef100_Q9V6X7
UniRef90:
UniRef90_Q9V6X7
UniRef50:
UniRef50_Q9V6X7
UniGene:
Dm.30916
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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