| Type | Description |
|---|---|
| Definition | interleukin 1 receptor associated kinase 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:31:00 | IRAK2 is associated with systemic lupus erythematosus risk. | 31650390 |
| 2019-12-07 10:06:00 | Both IRAK2 and TLR10 play important roles in the onset and development of Hashimoto's disease. | 31073143 |
| 2019-09-21 12:09:00 | these findings demonstrate a novel mechanism of interplays for the different branches of ER stress signaling network and highlight IRAK2 as a potential tumor suppressor to counterbalance oncogenic Smurf1. | 29753111 |
| 2019-03-09 10:59:00 | Authors identified IRAK2 rs779901 C > T as a predictor of NSCLC OS, with a variant-allele (T) attributed hazards ratio (HR) of 0.78 [95% confidence interval (CI) = 0.67-0.91, P = 0.001] in the PLCO dataset, 0.84 (0.72-0.98, 0.031) in the Harvard dataset, and 0.81 (0.73-0.90, 1.08x10(-4) ) in the meta-analysis of these two GWAS datasets. | 29978465 |
| 2018-09-08 11:09:00 | This study for the first time ever reports the association of IRAK2 rs3844283, IRAK2 rs708035, and the corresponding haplotypes with rheumatoid arthritis. | 29129009 |
| Type | IDs |
|---|---|
| Synonymous | IRAK-2 |
| Gene |
UniProtKB-ID:
IRAK2_HUMAN
UniprotKB:
O43187
UniParc:
UPI000020AB17
EMBL:
AJ496794,
AK299033,
AF026273,
BC125184
Ensembl:
ENSG00000134070
KO:
hsa:3656
|
| Nucleutide sequences |
EMBL-CDS:
CAD43180.3,
AAB87669.1,
AAI25185.1,
BAG61108.1
Ensembl_TRS:
ENST00000256458
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000256458
RefSeq:
NP_001561.3
|
| Others |
UniRef100:
UniRef100_O43187
UniRef90:
UniRef90_O43187
UniRef50:
UniRef50_O43187
UniGene:
Hs.449207
CCDS:
CCDS33697.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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