| Type | Description |
|---|---|
| Definition | polymerase PB2 |
| Date | Results | Publications |
|---|---|---|
| 2019-07-06 12:02:00 | Out-of-frame deletions in the polymerase basic 2 (PB2) gene of the H3N2 virus are detected after initiation of treatment with oseltamivir. Defective interferring-like viral PB2 RNA are detected in influenza positive respiratory samples. | 29448067 |
| 2018-11-24 10:11:00 | The results showed that the E627K or D701N substitutions in the PB2 subunit of CIV H3N2 enhanced polymerase activity, but these substitutions did not impact viral pathogenicity in mice or beagles. | 29885803 |
| 2015-11-21 11:33:00 | PB2-K526R interacts with nuclear export protein and our results suggest that it contributes to enhance replication for certain influenza virus subtypes, particularly in combination with 627K. | 25409547 |
| 2015-08-15 11:27:00 | Data suggest that two human spliceosomal factors, SMU1 and RED, are recruited to control expression and alternative splicing of viral exportins via PB2 (polymerase PB2) of influenza A virus (H3N2) and are required for efficient viral multiplication. | 24945353 |
| 2015-01-31 10:50:00 | Data indicate that a mutation in the valine/arginine/glycine (VRG) motif site inhibited acetyl-CoA interaction, RNA polymerase activity, and viral replication. | 25063805 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
Q464A9_9INFA
UniprotKB:
Q464A9
UniParc:
UPI00005762BF
EMBL:
CY002071
KO:
vg:3655161
|
| Nucleutide sequences |
EMBL-CDS:
AAZ38626.1
|
| Protein sequencees |
RefSeq:
YP_308849.1
|
| Others |
UniRef100:
UniRef100_A2CGX2
UniRef90:
UniRef90_P03427
UniRef50:
UniRef50_P03427
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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