例如:"NBL1", "4681", "drought"
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3655154 NA

3655154

NA

neuraminidase

protein-coding

Influenza A virus (A/New York/392/2004(H3N2))

基因描述

Type Description
Definition neuraminidase

研究结论

Date Results Publications
2020-08-15 19:08:00 Neuraminidase antigenic drift of H3N2 clade 3c.2a viruses alters virus replication, enzymatic activity and inhibitory antibody binding. 32598381
2019-07-06 12:02:00 The viruses harboring the 245-248 deletion in the neuraminidase gene were still present after discontinuation of oseltamivir treatment and passages in cell cultures, indicating a potential risk for transmission of the deleted virus. Deletion in the neuramindase gene of influenza A H3N2 induce antiviral resistance. Influenza A H3N2 virus with antiviral resistance deletion retains fitness. 29448067
2016-04-23 11:21:00 we also demonstrate that NA[neuraminidase] mutations at residue Q136 can confer reduced zanamivir, peramivir or laninamivir susceptibility. 26608955
2016-04-16 11:51:00 No additional NA amino acid sequences related to the IC50 of the four NA inhibitors was found 26630841
2015-11-07 10:39:00 FLUAV strains can counteract tetherin via their HA and NA proteins identifies these proteins as novel tetherin antagonists and indicates that HA/NA-dependent inactivation of innate defenses may contribute to the efficient spread of pandemic FLUAV. 26109730

名称对应

Type IDs
Gene
UniProtKB-ID: Q464B6_9INFA
UniprotKB: Q464B6
UniParc: UPI00005762B2
EMBL: CY002066
KO: vg:3655154
Nucleutide sequences
EMBL-CDS: AAZ38619.1
Protein sequencees
RefSeq: YP_308842.1
Others
UniRef100: UniRef100_Q464D8
UniRef90: UniRef90_P06818
UniRef50: UniRef50_P06820

全选

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