| Type | Description |
|---|---|
| Definition | DJ-1alpha |
| Date | Results | Publications |
|---|---|---|
| 2017-09-23 12:30:00 | trimethyl isocitrate (TIC), a cell permeable isocitrate, protected mammalian DJ-1 null DA cells from oxidative stress in an IDH-dependent manner. These results suggest that isocitrate and its derivatives are novel treatments for Parkinson's disease associated with DJ-1 dysfunction | 28827794 |
| 2010-07-05 11:42:00 | Flies deleted for DJ-1 manifest similar defects as pink1 and parkin mutants: male sterility, shortened lifespan, and reduced climbing ability. | 20457924 |
| 2010-01-21 00:00:00 | Data show that DJ-1 is a key negative regulator of PTEN that may be a useful prognostic marker for cancer. | 15766664 |
| 2010-01-21 00:00:00 | Overexpression of DJ-1alpha in dopaminergic neurons is sufficient to confer protection against paraquat insult. | 16139214 |
| Type | IDs |
|---|---|
| Synonymous | CG6646, DJ-1, DJ-1A, DJ-1a, Dj-1alpha, Dmel\CG6646 |
| Gene |
UniProtKB-ID:
DJ1A_DROME
UniprotKB:
A1Z9J4
UniParc:
UPI0000075FC7
EMBL:
AE013599
EnsemblGenome:
FBgn0033885
KO:
dme:Dmel_CG6646
|
| Nucleutide sequences |
EMBL-CDS:
AAF58316.2
Gene_ORFName:
CG6646
EnsemblGenome_TRS:
FBtr0087615
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0086741
RefSeq:
NP_610916.1
|
| Others |
UniRef100:
UniRef100_A1Z9J4
UniRef90:
UniRef90_A1Z9J4
UniRef50:
UniRef50_Q9VA37
UniGene:
Dm.30975
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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