| Type | Description |
|---|---|
| Definition | mitogen-activated protein kinase kinase kinase 5 |
| Date | Results | Publications |
|---|---|---|
| 2020-12-19 13:38:00 | ASK1 phosphorylation regulates astrocytic reactive gliosis in vitro and in vivo. | 31830507 |
| 2020-02-01 11:07:00 | Thioredoxin is regulated by the ASK-1/Trx/TXNIP axis to maintain cellular redox homeostasis and is linked to testicular ischemia reperfusion injury -induced spermatozoa apoptosis via the ASK-1/JNK/p38/survivin apoptosis pathway. | 31547465 |
| 2019-09-14 11:42:00 | ASK1 contributes to fibrosis and dysfunction in models of kidney disease. | 30024858 |
| 2019-03-16 13:04:00 | Selective ASK1 inhibition confers anti-hypertrophic and anti-fibrotic effects in cardiac cells, and anti-inflammation in monocytic cells. ASK1 inhibitors may represent novel therapeutic agents to alleviate cardiac remodelling post cardiac injury where hypertrophy, fibrosis and inflammation play critical roles. | 29277546 |
| 2018-09-15 11:49:00 | Activation of the TRAF1/ASK1/JNK/NF-kappaB signaling pathway is involved in the inflammation of SAP. Curcumin exerts anti-inflammatory effects by suppressing this proinflammatory pathway. | 29657313 |
| Type | IDs |
|---|---|
| Synonymous | Ask1, RGD1306565 |
| Gene | |
| Nucleutide sequences | |
| Protein sequencees |
RefSeq:
NP_001264623.1
|
| Others |
UniGene:
Rn.232064
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员