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36491 cnn

36491

cnn

centrosomin

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition centrosomin

研究结论

Date Results Publications
2020-02-08 10:58:00 These findings suggest that interactions between Spd-2, Polo and Cnn form a positive feedback loop that drives the dramatic expansion of the mitotic pericentriolar material in fly embryos. 31498081
2018-08-04 11:03:00 Drosophila centrosomin (cnn) expresses two major protein variants: the centrosomal form (CnnC) and a non-centrosomal form in testes (CnnT). CnnC is established as essential for functional centrosomes, the major MTOCs in animal cells. CnnT is expressed exclusively in testes and localizes to giant mitochondria in spermatids. 28669756
2018-02-17 10:48:00 suggest an expanded model where during interphase CM2 interacts with pericentrin-like-protein to form a layer of centrosomin around the centriole wall and that at the onset of mitosis this population acts as a nucleation site of intramolecular centrosomin interactions that support the expansion into the metaphase matrix 29315319
2017-08-12 11:16:00 Study shows that cnn exon1A-encoded proteins interact with Polo at 2 residues and that this interaction is required for polar body and pericentriolar matrix formation in syncytial embryos. 27096551
2016-07-16 11:13:00 During pericentriolar matrix formation exon 1A Cnn-Long Form proteins likely bind Polo kinase before phosphorylation by Polo for Cnn transport to the centrosome. 26447129

名称对应

Type IDs
Synonymous CG 4832, CG18370, CG4832, CNN, Cnn, Cnn1, Dmel\CG4832, cen, mat(2)syn-C, mat(2)synHK21, mfs, obv
Gene
UniProtKB-ID: CNN_DROME, A0A0B4K7N9_DROME, A0A0B4K863_DROME, A1Z9D4_DROME, A1Z9D3_DROME, A0A0B4K6Z9_DROME, A0A0B4K773_DROME
UniprotKB: P54623, A0A0B4K7N9, A0A0B4K863, A1Z9D4, A1Z9D3, A0A0B4K6Z9, A0A0B4K773
UniParc: UPI000008502E, UPI0000075EDB, UPI000237F4D4, UPI000007990D, UPI000264EC51, UPI000264EC50, UPI000007CE4E, UPI0000682709, UPI00001E0C5F, UPI000264EC52
EMBL: BT001287, BT010053, BT003808, AE013599, U35621, BT021269
EnsemblGenome: FBgn0013765
KO: dme:Dmel_CG4832
Nucleutide sequences
EMBL-CDS: AAN71043.1, AAO41491.1, AAQ22522.1, ACZ94414.1, AAM68579.1, AAF58376.2, AAF58375.1, AAB82065.1, AAX33417.1, AFH08050.1, AFH08048.1, AFH08049.1, AFH08047.1, AAX52706.1, ABC66061.1, AFH08045.1, AFH08046.1
Gene_ORFName: CG4832, Dmel_CG4832, CG4832, Dmel_CG4832, CG4832, Dmel_CG4832, CG4832, CG4832, Dmel_CG4832, Dmel_CG4832, CG4832, CG4832, Dmel_CG4832
EnsemblGenome_TRS: FBtr0306635, FBtr0309892, FBtr0309893, FBtr0087703, FBtr0309889, FBtr0301395, FBtr0087704, FBtr0309892, FBtr0309893, FBtr0087704, FBtr0309891, FBtr0100654, FBtr0100656, FBtr0309888, FBtr0309890
Protein sequencees
EnsemblGenome_PRO: FBpp0297590, FBpp0290609, FBpp0301627, FBpp0086822, FBpp0301626, FBpp0301623, FBpp0086823, FBpp0301627, FBpp0301626, FBpp0086823, FBpp0301625, FBpp0100116, FBpp0100117, FBpp0301622, FBpp0301624
RefSeq: NP_001033944.1, NP_001246295.1, NP_001014523.1, NP_725298.1, NP_001246294.1, NP_477084.1, NP_001246292.1, NP_001246293.1, NP_001163141.1, NP_725297.1, NP_001246291.1, NP_001246296.1
Others
UniRef100: UniRef100_A1Z9D3, UniRef100_A0A0B4K6Z9, UniRef100_A0A0B4K7N9, UniRef100_A1Z9D4, UniRef100_P54623, UniRef100_A0A0B4K863, UniRef100_A0A0B4K773
UniRef90: UniRef90_P54623-4, UniRef90_P54623, UniRef90_A1Z9D4, UniRef90_P54623-5
UniRef50: UniRef50_P54623-4, UniRef50_A1Z9D4, UniRef50_P54623
UniGene: Dm.4773

全选

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