| Type | Description |
|---|---|
| Definition | tripeptidyl-peptidase II |
| Date | Results | Publications |
|---|---|---|
| 2013-04-06 12:19:00 | Previously unknown differences between TPP II orthologues and subtilisin as well as features that might be conserved within the entire family of subtilisin-like serine peptidases. | 22266401 |
| 2011-12-17 11:40:00 | a systematic kinetic analysis of wild type Drosophila melanogaster TPPII and five point mutants of the double-Glu-motif (E312/E343) involving natural substrates were performed. | 21946061 |
| 2010-09-06 12:15:00 | The structure suggests a model for activation of TPP II involving the relocation of a flexible loop and a repositioning of the active-site serine, coupling it to holocomplex assembly and active-site sequestration. | 20676100 |
| 2010-01-21 00:00:00 | The 150 kDa subunits of TPPII form a superstructure composed of 2 segmented & twisted strands. Each strand is 12.5 nm in width & composed of 11 segments that enclose a central channel. | 12426370 |
| 2010-01-21 00:00:00 | the unique spindle form of the holo-complex of TPP II represents an assembly motif stabilizing a highly active state | 16799156 |
| Type | IDs |
|---|---|
| Synonymous | CG3991, Dmel\CG3991, TPP II, TPP2, TPPII, anon-WO0118547.127, dTPP II, dTPPII, l(2)k14301 |
| Gene |
UniProtKB-ID:
TPP2_DROME,
A0A0B4LF88_DROME,
A0A0B4LGC0_DROME
UniprotKB:
Q9V6K1,
A0A0B4LF88,
A0A0B4LGC0
UniParc:
UPI0000083289,
UPI0002B8CDFD,
UPI000000BF78
EMBL:
AF035251,
BT001404,
BT044288,
BT003260,
AE013599
EnsemblGenome:
FBgn0020370
KO:
dme:Dmel_CG3991
|
| Nucleutide sequences |
EMBL-CDS:
AAM68593.1,
AAO25017.1,
AAC28563.1,
ACH92353.1,
AAF58422.2,
AAN71159.1,
AHN56175.1,
AHN56174.1
Gene_ORFName:
CG3991,
CG3991,
Dmel_CG3991,
Dmel_CG3991,
CG3991
EnsemblGenome_TRS:
FBtr0344199,
FBtr0087775,
FBtr0087774,
FBtr0339755,
FBtr0087775,
FBtr0344199
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0310608,
FBpp0086887,
FBpp0086888,
FBpp0308802,
FBpp0310608,
FBpp0086888
RefSeq:
NP_477247.1,
NP_001286377.1,
NP_725252.1,
NP_001286376.1
|
| Others |
UniRef100:
UniRef100_Q9V6K1,
UniRef100_A0A0B4LF88
UniRef90:
UniRef90_Q9V6K1
UniRef50:
UniRef50_Q9V6K1
UniGene:
Dm.7374
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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