| Type | Description |
|---|---|
| Definition | protein arginine methyltransferase 5 |
| Date | Results | Publications |
|---|---|---|
| 2020-09-05 13:56:00 | Maintenance of SOX9 stability and ECM homeostasis by selenium-sensitive PRMT5 in cartilage. | 30858101 |
| 2015-11-13 09:36:00 | These data provide the first direct experimental evidence that PRMT5, a type II arginine methylase, is involved in the control of transcription and proliferation. | 12101096 |
| 2012-03-10 11:43:00 | analysis of structural insights into protein arginine symmetric dimethylation by PRMT5 | 22143770 |
| 2012-03-03 10:27:00 | CpG-rich islands within the Id2 and Id4 genes were bound by PRMT5 and were hypomethylated in PRMT5-deficient cells, suggesting that PRMT5 plays a role in gene silencing during glial cell | 22041901 |
| 2012-01-14 10:23:00 | Protein arginine methyltransferase 5 regulates ERK1/2 signal transduction amplitude and cell fate through CRAF. | 21917714 |
| Type | IDs |
|---|---|
| Synonymous | Hrmt1l5, Skb1 |
| Gene |
UniProtKB-ID:
D4A0E8_RAT
UniprotKB:
D4A0E8
UniParc:
UPI00001D0E97
EMBL:
AABR07072452,
CH474049
Ensembl:
ENSRNOG00000012046
KO:
rno:364382
|
| Nucleutide sequences |
EMBL-CDS:
EDM14174.1
Gene_ORFName:
rCG_23370
Ensembl_TRS:
ENSRNOT00000016302
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000016302
RefSeq:
NP_001102337.2
|
| Others |
UniRef100:
UniRef100_D4A0E8
UniRef90:
UniRef90_O14744
UniRef50:
UniRef50_O14744
UniGene:
Rn.101808
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 30858101 |
Maintenance of SOX9 stability and ECM homeostasis by selenium-sensitive PRMT5 in cartilage. Osteoarthritis Cartilage M Sun , S Hussain , Y Hu , J Yan , Z Min , X Lan , Y Guo , Y Zhao , H Huang , M Feng , Y Han , F Zhang , W Zhu , L Meng , D Li , J Sun , S Lu |
2019-06-01 | - |
| 26700805 |
SMN and symmetric arginine dimethylation of RNA polymerase II C-terminal domain control termination. Nature Dorothy Yanling Zhao , Gerald Gish , Ulrich Braunschweig , Yue Li , Zuyao Ni , Frank W Schmitges , Guoqing Zhong , Ke Liu , Weiguo Li , Jason Moffat , Masoud Vedadi , Jinrong Min , Tony J Pawson , Benjamin J Blencowe , Jack F Greenblatt |
2016-01-07 |
PRMT5,
XRN2,
SETX,
POLR2A,
POLR2D,
SMN1,
SMN2,
TDRD3
|
| 26554819 |
The protein arginine methyltransferase PRMT5 promotes D2-like dopamine receptor signaling. Sci Signal Neah Likhite , Christopher A Jackson , Mao-Shih Liang , Michelle C Krzyzanowski , Pedro Lei , Jordan F Wood , Barbara Birkaya , Kerry L Michaels , Stelios T Andreadis , Stewart D Clark , Michael C Yu , Denise M Ferkey |
2015-11-10 | - |
| 25284789 |
Cell Rep Hiroki Takai , Koji Masuda , Tomohiro Sato , Yuriko Sakaguchi , Takeo Suzuki , Tsutomu Suzuki , Ryo Koyama-Nasu , Yukiko Nasu-Nishimura , Yuki Katou , Haruo Ogawa , Yasuyuki Morishita , Hiroko Kozuka-Hata , Masaaki Oyama , Tomoki Todo , Yasushi Ino , Akitake Mukasa , Nobuhito Saito , Chikashi Toyoshima , Katsuhiko Shirahige , Tetsu Akiyama |
2014-10-09 |
PRMT5,
ERH,
CHTOP,
PRMT1,
MBD1,
WDR77,
TET1
|
| 24583552 |
Readers of histone methylarginine marks. Biochim. Biophys. Acta Sitaram Gayatri , Mark T Bedford |
2014-08-01 |
LOC100911617,
Prmt7,
Carm1,
Prmt5,
Prmt2,
Prmt1
|
| 23048031 |
J Biol Chem Alexandra Chittka , Justyna Nitarska , Ursula Grazini , William D Richardson |
2012-12-14 | - |
| 23071334 |
Crystal structure of the human PRMT5:MEP50 complex. Proc. Natl. Acad. Sci. U.S.A. Stephen Antonysamy , Zahid Bonday , Robert M Campbell , Brandon Doyle , Zhanna Druzina , Tarun Gheyi , Bomie Han , Louis N Jungheim , Yuewei Qian , Charles Rauch , Marijane Russell , J Michael Sauder , Stephen R Wasserman , Kenneth Weichert , Francis S Willard , Aiping Zhang , Spencer Emtage |
2012-10-30 |
PRMT5,
WDR77
|
| 22871113 |
Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis. J. Proteome Res. Chan Hyun Na , Drew R Jones , Yanling Yang , Xusheng Wang , Yanji Xu , Junmin Peng |
2012-09-07 |
Rab1b,
Tmem59,
Msh6,
LOC100360426,
Sncb,
Csnk1a1,
Magi2,
Cxcl2,
Dnm1l,
Gng3,
Hcn2,
Clasp2,
Ubqln1,
Gne,
Stx1a,
Txn1,
Sec14l2,
Gripap1,
Mprip,
Slc6a9,
Ralb,
Ap2m1,
Nrxn2,
Slc17a7,
Vcp,
Cap2,
Dlgap2,
Lmnb1,
Trim28,
Epb41l3,
Ube2n,
Gp1bb,
Nup155,
Bin1,
Rpl6,
H3f3b,
Nlgn2,
Prdx1,
Psmc4,
Psmc1,
Epn1,
Ppp2r1a,
Hnrnpk,
Lrrc7,
Txnip,
Uba3,
Sv2b,
Tpm3,
Sv2a,
Atp6v1b2,
Rps20,
Slc8a2,
Rps3,
Faf1,
Ap2b1,
Dnm1,
Cacng8,
Cdk5,
Txnl1,
Ggt7,
Prkcd,
Palm,
Atp2c1,
Dynlrb1,
Kcnh7,
Xpnpep1,
Atxn10,
Kcnq2,
Cry2,
Rab3c,
Ndrg2,
Camk2g,
Pabpc1,
Eef1a1,
Slc12a5,
Acsbg1,
Tmem176b,
Nme1,
Tecr,
Syngap1,
Hip1,
Gpm6b,
Ehd4,
Rasgrf1,
Plpp3,
Stip1,
Caly,
Aldoa,
Aldoc,
Atp1a1,
Atp1a2,
Atp1a3,
Atp2b2,
Cacna1c,
Calm1,
Camk2d,
Ckb,
Eno1,
Gapdh
|
| 22269951 |
Mol. Cell. Biol. Smarajit Bandyopadhyay , Daniel P Harris , Gregory N Adams , Gregory E Lause , Anne McHugh , Emily G Tillmaand , Angela Money , Belinda Willard , Paul L Fox , Paul E Dicorleto |
2012-04-01 |
PRMT5,
HOXA9,
SELE,
VCAM1
|
| 22365833 |
Dynamic protein-protein interaction wiring of the human spliceosome. Mol. Cell Anna Hegele , Atanas Kamburov , Arndt Grossmann , Chrysovalantis Sourlis , Sylvia Wowro , Mareike Weimann , Cindy L Will , Vlad Pena , Reinhard Lührmann , Ulrich Stelzl |
2012-02-24 |
PQBP1,
RBM7,
RBM5,
SF3B4,
CWC27,
SAP18,
SMNDC1,
BCAS2,
SF3A1,
RACK1,
PRMT5,
CD2BP2,
PPIE,
PPIH,
SYNCRIP,
DDX17,
CHERP,
SLU7,
PRPF8,
KHDRBS3,
KHDRBS1,
CELF1,
SRSF10,
RNPS1,
SF3A3,
HNRNPA0,
SF3B2,
SNRNP27,
HNRNPUL1,
LSM6,
DDX42,
U2AF2,
TOE1,
CIRBP,
FRA10AC1,
CLNS1A,
TTC14,
CCDC12,
DDX5,
DHX8,
DHX9,
DHX15,
ELAVL1,
PUF60,
RALY,
NCBP2,
SNW1,
ACIN1,
SNRNP200,
U2SURP,
SF3B3,
SF3B1,
SRRM2,
RBFOX2,
LSM5,
PPIL2,
PRPF6,
FRG1,
LSM4,
FAM32A,
PRPF31,
PABPC1,
GPKOW,
LSM3,
RBMX,
HTATSF1,
PRPF19,
SAP30BP,
TRA2A,
HNRNPA1,
HNRNPAB,
HNRNPC,
HNRNPD,
HNRNPF,
HNRNPH1,
HNRNPH2,
HNRNPH3,
HNRNPK,
HNRNPU,
HSPA8,
HSPB1,
IK,
ILF3,
JUP,
MAGOH,
MFAP1,
HNRNPM,
NCBP1,
SNU13,
YBX1,
PCBP1,
PCBP2,
CRNKL1,
CDC40,
DDX41,
CWC15,
SRRT,
RBMX2,
SF3B6
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
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|---|---|---|
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