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363909 Caln1

363909

Caln1

calneuron 1

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition calneuron 1

研究结论

Date Results Publications
2016-01-16 12:23:00 The protein is most abundant in Purkinje cells of the cerebellum and principal neurons of the cortex and limbic brain whereas no expression in glial cells is apparent. 26116628
2012-10-20 10:51:00 NHE1 directly binds to calcineurin A and activates downstream NFAT signaling, leading to cardiomyocyte hypertrophy 22688515
2010-01-21 00:00:00 calneuron-1 and calneuron-2 physically associate with PI-4Kbeta, inhibit the enzyme profoundly at resting and low calcium levels, and negatively interfere with Golgi-to-plasma membrane trafficking. 19458041
2010-01-21 00:00:00 Calneurons have a different EF-hand organization than other calcium sensor proteins, are prominently expressed in neurons and will presumably bind Ca2+ with higher affinity than caldendrin. 17055077
2010-01-21 00:00:00 These results suggest that CalnI attenuates Ca(2+) channel activity and that its subcellular localization is important for this effect. 19682431

名称对应

Type IDs
Gene
UniProtKB-ID: CABP8_RAT, Q06BI2_RAT
UniprotKB: Q06BI3, Q06BI2
UniParc: UPI000000414C, UPI00001F2BAD
EMBL: DQ914829, AABR07035980, AABR07035978, AABR07035977, AABR07035979, DQ914830, AABR07035976
Ensembl: ENSRNOG00000000886
KO: rno:363909
Nucleutide sequences
EMBL-CDS: ABI94064.1, ABI94065.1
Ensembl_TRS: ENSRNOT00000001185
Protein sequencees
Ensembl_PRO: ENSRNOP00000001185
RefSeq: XP_017453896.1, XP_017453895.1, XP_017453894.1, XP_017453898.1, XP_017453897.1, NP_001070669.1, XP_006249305.1
Others
UniRef100: UniRef100_Q9JJG7, UniRef100_F8WHE1
UniRef90: UniRef90_F8WHE1, UniRef90_Q9JJG7
UniRef50: UniRef50_F1PZV0, UniRef50_Q9JJG7
UniGene: Rn.202895

全选

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研究热度

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