| Type | Description |
|---|---|
| Definition | insulin induced gene 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-24 14:07:00 | Investigation of the association between obesity and insulin-induced gene 1 polymorphism at 7q36.3 region in Uygur population in Xinjiang, China. | 31658356 |
| 2020-06-06 12:45:00 | the gluconeogenic enzyme PCK1 phosphorylates INSIG1/2 for lipogenesis; findings highlight the importance of the protein kinase activity of PCK1 in the activation of SREBPs, lipogenesis and the development of hepatocellular carcinoma | 32322062 |
| 2019-06-29 11:08:00 | INSIG1 functions as a sentinel responsive to HIV-1 production and inhibits HIV-1 replication by degrading Gag, a process occurring at intracellular membrane sites such as the endoplasmic reticulum and endosomes where both INSIG1 and Gag may be located. | 30563842 |
| 2019-01-19 11:45:00 | Knock down of FADS1 did not significantly change cholesterol efflux (p=0.70), but knockdown of INSIG1 and LDLR resulted in highly significant reduction of the efflux to HDL (67% and 75% of control, respectively, p<0.001). | 30118702 |
| 2018-01-06 11:37:00 | INSIG1 variation may contribute to statin-induced changes in plasma triglycerides in a sex-specific manner. | 26927283 |
| Type | IDs |
|---|---|
| Synonymous | CL6 |
| Gene |
UniProtKB-ID:
INSI1_HUMAN,
F5H6P3_HUMAN,
A0A024RD68_HUMAN,
A4D2M9_HUMAN
UniprotKB:
O15503,
F5H6P3,
A0A024RD68,
A4D2M9
UniParc:
UPI000021CD0C,
UPI00000015DE,
UPI0001A81EE6,
UPI000021CD0B
EMBL:
CH236962,
BT007227,
U96876,
AK291675,
AC144652,
BC001880,
DN996424,
AC231970,
CH471149,
AY112745
Ensembl:
ENSG00000186480
KO:
hsa:3638
|
| Nucleutide sequences |
EMBL-CDS:
EAL23730.1,
EAX04530.1,
AAM44086.1,
EAL23729.1,
BAF84364.1,
AAH01880.1,
EAX04529.1,
AAB69121.1,
AAP35891.1,
EAX04532.1,
EAX04531.1,
EAL23728.1
Gene_ORFName:
hCG_1641980,
tcag7.832,
hCG_1641980
Ensembl_TRS:
ENST00000342407,
ENST00000340368,
ENST00000344756
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000344741,
ENSP00000344035,
ENSP00000340010
RefSeq:
NP_001333521.1,
NP_001333523.1,
NP_005533.2,
NP_001333520.1,
NP_938150.2,
NP_001333519.1,
NP_938151.1,
NP_001333522.1
|
| Others |
UniRef100:
UniRef100_F5H6P3,
UniRef100_A4D2M9,
UniRef100_O15503
UniRef90:
UniRef90_O15503,
UniRef90_F5H6P3
UniRef50:
UniRef50_F5H6P3,
UniRef50_O15503
UniGene:
Hs.520819
CCDS:
CCDS5938.1,
CCDS5939.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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