| Type | Description |
|---|---|
| Definition | NDP, norrin cystine knot growth factor |
| Date | Results | Publications |
|---|---|---|
| 2018-08-04 10:09:00 | Studied the influence of dendrobium nobile Lindley (DNL) extract and its bibenzyl component moscatilin on the expression of placental growth factor (PLGF) and Norrie disease protein (NDP) in hypoxia model in retinal cells. Found DNL and moscatilin are able to protect against retinal ischemic/hypoxic changes respectively by downregulating PLGF and upregulating NDP. | 29933759 |
| 2015-12-12 10:48:00 | The endogenously expressed Lgr4 may act as an antagonist molecule that helps to fine-tune the R-spondin/norrin-mediated Lgr4-Wnt signaling during gonadal development. | 25188337 |
| 2015-05-16 10:08:00 | Norrin upregulation protected blood-brain barrier integrity and improved outcome after subarachnoid hemorrhage. | 25550365 |
| 2012-01-14 11:12:00 | Norrin might regulate the decidual reaction and the placental angiogenesis along with the survival and the differentiation of luminal and glandular epithelial and decidual cells in rats. | 21899531 |
| 2010-05-31 11:24:00 | Norrin has pronounced neuroprotective properties on retinal neurons. The effects of Norrin involve activation of Wnt/beta-catenin signaling and subsequent induction of neurotrophic growth factors in Muller cells. | 20427659 |
| Type | IDs |
|---|---|
| Synonymous | Ndph, RGD1563968 |
| Gene |
UniProtKB-ID:
D3ZEP2_RAT
UniprotKB:
D3ZEP2
UniParc:
UPI0000024D31
EMBL:
AABR07073515,
AC097257,
CH474009
Ensembl:
ENSRNOG00000046042,
ENSRNOG00000002960
KO:
rno:100909913,
rno:363443
|
| Nucleutide sequences |
EMBL-CDS:
EDL97666.1
Gene_ORFName:
rCG_42843
Ensembl_TRS:
ENSRNOT00000003984,
ENSRNOT00000074275
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000003984,
ENSRNOP00000064536
RefSeq:
NP_001102284.1,
XP_017457590.1
|
| Others |
UniRef100:
UniRef100_P48744
UniRef90:
UniRef90_P48744
UniRef50:
UniRef50_Q00604
UniGene:
Rn.45519
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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