| Type | Description |
|---|---|
| Definition | heat shock protein 90 beta family member 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-09-21 10:06:00 | We found that GRP94 coimmunoprecipitated with proinsulin and that inhibition of GRP94 function and/or expression reduced glucose-dependent insulin secretion, shortened proinsulin half-life, and lowered intracellular proinsulin and insulin levels. | 30670477 |
| 2019-02-02 10:47:00 | We demonstrated that incubation of hepatocytes for 16 h with palmitic acid elevated cell death. Moreover, Western blot analyses demonstrated increased levels of the endoplasmic reticulum stress markers - glucose regulated protein 78 (GRP78), C/EBP homologous protein (CHOP), and glucose regulated protein 94 (GRP94). | 30486828 |
| 2019-01-05 10:09:00 | The results showed that both Unfolded Protein Response (Xbp-1, its spliced variant sXbp-1, Atf-6, Chop, and Grp94) and Toll like receptor (2, 3, 4, 7 and 9) genes were significantly upregulated in the hippocampi of rats who were exposed to restraint stress. | 29414031 |
| 2015-04-04 11:03:00 | The maintenance of Grp94 expression is sufficient to counter unloading atrophy and oxidative stress by mechanistically stabilizing nNOS-multiprotein complex at the myofiber sarcolemma. | 24093939 |
| 2014-08-09 12:24:00 | Hepatic expression of metallothionein I/II, glycoprotein 96, IL-6, and TGF- beta in rat strains contributed to different susceptibilities to experimental autoimmune encephalomyelitis. | 24489578 |
| Type | IDs |
|---|---|
| Synonymous | Grp94, Tra1 |
| Gene |
UniProtKB-ID:
ENPL_RAT
UniprotKB:
Q66HD0
UniParc:
UPI00001CFC32,
UPI000042AE80
EMBL:
BC081917,
CH473960
KO:
rno:362862
|
| Nucleutide sequences |
EMBL-CDS:
AAH81917.1,
EDM17052.1
|
| Protein sequencees |
RefSeq:
NP_001012197.2
|
| Others |
UniRef100:
UniRef100_Q66HD0
UniRef90:
UniRef90_P14625
UniRef50:
UniRef50_P14625
UniGene:
Rn.101146
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员