| Type | Description |
|---|---|
| Definition | bromodomain containing 4 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-13 13:15:00 | Bromodomain-containing protein 4 inhibition alleviates matrix degradation by enhancing autophagy and suppressing NLRP3 inflammasome activity in NP cells. | 31975410 |
| 2020-08-22 15:27:00 | The BD2 domain of BRD4 is a determinant in EndoMT and vein graft neointima formation. | 31075399 |
| 2020-07-25 10:27:00 | this study illustrates that microglial BRD4 level is increased after spinal cord injury (SCI) and BRD4 inhibition is able to suppress M1 polarization and pro-inflammatory cytokine production in microglia which ultimately promotes functional recovery after SCI. | 30809946 |
| 2019-06-01 12:28:00 | BRD4 serves an important role in the pathogenesis of HGinduced cardiomyocyte hypertrophy through the AKT pathway. | 30483785 |
| 2018-09-08 11:49:00 | Inhibition of BRD4 attenuated cardiomyocyte apoptosis via NF-kappaB pathway in myocardial infarction. | 29352508 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
D3ZGX8_RAT,
A0A0G2JYV0_RAT
UniprotKB:
D3ZGX8,
A0A0G2JYV0
UniParc:
UPI0003D08AD3,
UPI0000DA2C5A
EMBL:
AABR07055865,
AABR07055864
Ensembl:
ENSRNOG00000006770
KO:
rno:362844
|
| Nucleutide sequences |
Ensembl_TRS:
ENSRNOT00000008963,
ENSRNOT00000091368
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000008963,
ENSRNOP00000070799
RefSeq:
XP_008763392.1,
XP_006241136.1,
XP_006241134.1,
XP_008763393.2,
XP_017450405.1,
NP_001094373.1,
XP_008763395.1,
XP_006241135.1
|
| Others |
UniRef100:
UniRef100_A0A0G2JYV0,
UniRef100_D3ZGX8
UniRef90:
UniRef90_A0A0G2JYV0,
UniRef90_Q9ESU6
UniRef50:
UniRef50_O60885
UniGene:
Rn.12110
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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||||
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