| Type | Description |
|---|---|
| Definition | complement C5 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-11 12:30:00 | Evidence for a pivotal role of the C5a/C5aR1 axis in propagating renal injury in the development of diabetic kidney disease (DKD) by disrupting mitochondrial agility, thereby establishing a new immunometabolic signaling pathway in DKD. | 31624141 |
| 2019-03-09 11:55:00 | IL-1beta can increase C5a expression in RSC-364 cells, and C5a exerts a proinflammatory effect in RSC-364 cells. | 30092352 |
| 2018-10-20 11:12:00 | The expression of C5a was increased in synoviocytes and joint cartilage in the IM model. Proinflammatory cytokines, including TNFalpha and IL1beta were released in the activated synoviocytes via the induction of C5a, suggesting that C5a serves an important role in joint inflammatory processes. | 29956782 |
| 2017-07-22 12:47:00 | n the complex but clinically relevant DH model the local and systemic inflammatory immune response features both, C5-dependent and C5-independent characteristics. Activation of caspase-3 in lung tissue after DH was C5-dependent whereas local inflammation in lung tissue was C5-independent. | 27437704 |
| 2015-05-16 12:53:00 | Data indicate that absence of complement C3, complement C5 and Fc receptor subunit gamma (FcRgamma) does not impact autoantibody production in K/BxN mice. | 23237573 |
| Type | IDs |
|---|---|
| Synonymous | C5a, Hc, RGD1561905 |
| Gene | |
| Nucleutide sequences | |
| Protein sequencees |
RefSeq:
XP_003749503.2,
XP_001079130.2,
NP_444179.1,
XP_008760020.1
|
| Others |
UniGene:
Rn.21259
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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