| Type | Description |
|---|---|
| Definition | cornichon family AMPA receptor auxiliary protein 2 |
| Date | Results | Publications |
|---|---|---|
| 2012-06-09 10:26:00 | Mammalian AMPARs commandeer CNIH-2 for use as a bona fide auxiliary subunit that is able to modify receptor signaling. | 22292017 |
| 2011-08-06 11:13:00 | CNIH-2 modulates neuronal AMPA receptor auxiliary subunit assembly by regulating the number of transmembrane AMPA receptor regulatory proteins within an AMPA receptor complex to modulate receptor gating and pharmacology. | 21543622 |
| 2010-01-21 00:00:00 | findings show that the majority of AMPARs in the brain are coassembled with CNIH-2 & CNIH-3; cornichons increase surface expression of AMPARs, & alter channel gating by markedly slowing deactivation & desensitization kinetics | 19265014 |
| Type | IDs |
|---|---|
| Synonymous | CNIH-2, Cnih3, RGD1304930 |
| Gene |
UniProtKB-ID:
CNIH2_RAT
UniprotKB:
Q5BJU5
UniParc:
UPI000000DC89
EMBL:
BC091325
Ensembl:
ENSRNOG00000020247
KO:
rno:361705
|
| Nucleutide sequences |
EMBL-CDS:
AAH91325.1
Ensembl_TRS:
ENSRNOT00000027421
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000027421
RefSeq:
XP_017444929.1,
NP_001020303.1,
XP_017444928.1,
XP_017444926.1,
XP_008758376.1,
XP_017444927.1
|
| Others |
UniRef100:
UniRef100_Q6PI25
UniRef90:
UniRef90_Q6PI25
UniRef50:
UniRef50_Q6PI25
UniGene:
Rn.18785
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 24853943 |
Cornichon2 dictates the time course of excitatory transmission at individual hippocampal synapses. Neuron Sami Boudkkazi , Aline Brechet , Jochen Schwenk , Bernd Fakler |
2014-05-21 | - |
| 24094107 |
Cornichons control ER export of AMPA receptors to regulate synaptic excitability. Neuron Penelope J Brockie , Michael Jensen , Jerry E Mellem , Erica Jensen , Tokiwa Yamasaki , Rui Wang , Dane Maxfield , Colin Thacker , Frédéric Hoerndli , Patrick J Dunn , Susumu Tomita , David M Madsen , Andres V Maricq |
2013-10-02 |
Cnih2,
sol-1,
glr-1,
eat-4,
cni-1,
stg-2
|
| 22292017 |
AMPA receptors commandeer an ancient cargo exporter for use as an auxiliary subunit for signaling. PLoS ONE Nadine Harmel , Barbara Cokic , Gerd Zolles , Henrike Berkefeld , Veronika Mauric , Bernd Fakler , Valentin Stein , Nikolaj Klöcker |
2012-01-01 | - |
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 21543622 |
J Neurosci Martin B Gill , Akihiko S Kato , Matthew F Roberts , Hong Yu , He Wang , Susumu Tomita , David S Bredt |
2011-05-04 | - |
| 21172611 |
Hippocampal AMPA receptor gating controlled by both TARP and cornichon proteins. Neuron Akihiko S Kato , Martin B Gill , Michelle T Ho , Hong Yu , Yuan Tu , Edward R Siuda , He Wang , Yue-Wei Qian , Eric S Nisenbaum , Susumu Tomita , David S Bredt |
2010-12-22 | - |
| 20805473 |
Proc. Natl. Acad. Sci. U.S.A. Yun Shi , Young Ho Suh , Aaron D Milstein , Kaname Isozaki , Sabine M Schmid , Katherine W Roche , Roger A Nicoll |
2010-09-14 |
Cacng2,
Cnih2,
Cnih2,
Gria1,
Cacng2,
CACNG2,
CNIH3,
CNIH2,
GRIA1,
CACNG8
|
| 19265014 |
Functional proteomics identify cornichon proteins as auxiliary subunits of AMPA receptors. Science Jochen Schwenk , Nadine Harmel , Gerd Zolles , Wolfgang Bildl , Akos Kulik , Bernd Heimrich , Osamu Chisaka , Peter Jonas , Uwe Schulte , Bernd Fakler , Nikolaj Klöcker |
2009-03-06 | - |
| 15489334 |
Genome Res. Daniela S Gerhard , Lukas Wagner , Elise A Feingold , Carolyn M Shenmen , Lynette H Grouse , Greg Schuler , Steven L Klein , Susan Old , Rebekah Rasooly , Peter Good , Mark Guyer , Allison M Peck , Jeffery G Derge , David Lipman , Francis S Collins , Wonhee Jang , Steven Sherry , Mike Feolo , Leonie Misquitta , Eduardo Lee , Kirill Rotmistrovsky , Susan F Greenhut , Carl F Schaefer , Kenneth Buetow , Tom I Bonner , David Haussler , Jim Kent , Mark Kiekhaus , Terry Furey , Michael Brent , Christa Prange , Kirsten Schreiber , Nicole Shapiro , Narayan K Bhat , Ralph F Hopkins , Florence Hsie , Tom Driscoll , M Bento Soares , Tom L Casavant , Todd E Scheetz , Michael J Brown-stein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Yulan Piao , Dawood B Dudekula , Minoru S H Ko , Koichi Kawakami , Yutaka Suzuki , Sumio Sugano , C E Gruber , M R Smith , Blake Simmons , Troy Moore , Richard Waterman , Stephen L Johnson , Yijun Ruan , Chia Lin Wei , S Mathavan , Preethi H Gunaratne , Jiaqian Wu , Angela M Garcia , Stephen W Hulyk , Edwin Fuh , Ye Yuan , Anna Sneed , Carla Kowis , Anne Hodgson , Donna M Muzny , John McPherson , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madari , Alice C Young , Keith D Wetherby , Steven J Granite , Peggy N Kwong , Charles P Brinkley , Russell L Pearson , Gerard G Bouffard , Robert W Blakesly , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Malachi Griffith , Obi L Griffith , Martin I Krzywinski , Nancy Liao , Ryan Morin , Ryan Morrin , Diana Palmquist , Anca S Petrescu , Ursula Skalska , Duane E Smailus , Jeff M Stott , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Robert A Holt , Agnes Baross , Marco A Marra , Sandra Clifton , Kathryn A Makowski , Stephanie Bosak , Joel Malek , MGC Project Team |
2004-10-01 |
Ldlrap1,
Dnajc3,
Rnaset2a,
Btnl1,
Isg15,
Cyp3a41b,
Ly6c2,
Ccl21b,
Eif3j2,
Mup18,
Lrrc19,
Rcc1,
1700047I17Rik2,
Pcsk9,
Adat3,
Tdrd7,
Sco2,
Gpr153,
Pafah2,
Gm44504,
H6pd,
Adprhl2,
Gpn2,
Rusc2,
Stx12,
Ppp1r8,
Smpdl3b,
Fam46b,
Bsdc1,
Slc44a1,
Zfand2a,
Rubcn,
Kifc1,
Pifo,
C030017K20Rik,
Cbarp,
Rpl5,
Micalcl,
Atg14,
Lrrc8c,
Noc4l,
Nsun5,
Psph,
Trrap,
Mapre3,
Ube3c,
Tbc1d14,
Hscb,
Tyw1,
Emilin1,
Rab28,
Pot1a,
Parp11,
Tada3,
Tra2a,
Brk1,
Fbxl14,
Phrf1,
Plekha1,
Gm21975,
Ric8a,
Mob2,
Prkd2,
Ccp110,
Vrk3,
Grwd1,
Nlrp6,
Trim68,
Psip1,
Spred3,
Faap24,
Ints4,
Rrp8,
Unc45a,
Igflr1,
Sf3b3,
D8Ertd738e,
Usb1,
Champ1,
Smim19,
Exoc8,
Gadd45gip1,
Phkb,
Dohh,
Fam192a,
Enkd1,
Taf5l,
Zdhhc7,
Snapc2,
Ak6,
Gpat4,
Dcun1d2,
Ankrd10,
Cog4,
Hinfp,
Lars2,
Xylb,
Imp3,
Cmtm7
|
| 12477932 |
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. U.S.A. Robert L Strausberg , Elise A Feingold , Lynette H Grouse , Jeffery G Derge , Richard D Klausner , Francis S Collins , Lukas Wagner , Carolyn M Shenmen , Gregory D Schuler , Stephen F Altschul , Barry Zeeberg , Kenneth H Buetow , Carl F Schaefer , Narayan K Bhat , Ralph F Hopkins , Heather Jordan , Troy Moore , Steve I Max , Jun Wang , Florence Hsieh , Luda Diatchenko , Kate Marusina , Andrew A Farmer , Gerald M Rubin , Ling Hong , Mark Stapleton , M Bento Soares , Maria F Bonaldo , Tom L Casavant , Todd E Scheetz , Michael J Brownstein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Christa Prange , Sam S Raha , Naomi A Loquellano , Garrick J Peters , Rick D Abramson , Sara J Mullahy , Stephanie A Bosak , Paul J McEwan , Kevin J McKernan , Joel A Malek , Preethi H Gunaratne , Stephen Richards , Kim C Worley , Sarah Hale , Angela M Garcia , Laura J Gay , Stephen W Hulyk , Debbie K Villalon , Donna M Muzny , Erica J Sodergren , Xiuhua Lu , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madan , Alice C Young , Yuriy Shevchenko , Gerard G Bouffard , Robert W Blakesley , Jeffrey W Touchman , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Martin I Krzywinski , Ursula Skalska , Duane E Smailus , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Marco A Marra , Mammalian Gene Collection Program Team |
2002-12-24 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
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| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
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