| Type | Description |
|---|---|
| Definition | IQ motif containing GTPase activating protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-25 10:44:00 | IQGAP1 not only exerts a crucial role in microvascular endothelium barrier but also plays an important role in inflammation | 32364766 |
| 2019-07-13 10:41:00 | In cultured rat aortic SMCs, PDGF stimulation rapidly promoted ATP7A association with IQGAP1 and Rac1 and their translocation to the lipid rafts and leading edge. Cotransfection assay revealed that ATP7A directly bound to NH2-terminal domain of IQGAP1 | 30257103 |
| 2019-04-20 11:44:00 | These data are consistent with a model in which IQGAP1 cleavage is regulated by acetylation of the cleavage sites. Activation of ERK1/2 by ceramide, known to increase lysine acetylation, appears to be mediated by acetylation-dependent stabilization of IQGAP1. | 28839270 |
| 2014-07-26 12:42:00 | IQGAP1 contributes to AngII-induced apoptosis of podocytes by interacting with the ERK1/2 signaling protein | 24247724 |
| 2014-02-22 12:13:00 | Caveolin-1 and IQGAP1 are required for phosphorylation of the actin associated pool of extracellular signal regulated kinase 1 and 2 (ERK1/2) in response to protein kinase C activation. | 23987506 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
G3V7Q7_RAT
UniprotKB:
G3V7Q7
UniParc:
UPI000154F489
EMBL:
AABR07004428,
CH473980
Ensembl:
ENSRNOG00000012002
KO:
rno:361598
|
| Nucleutide sequences |
EMBL-CDS:
EDM08655.1
Gene_ORFName:
rCG_24856
Ensembl_TRS:
ENSRNOT00000018021
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000018021
RefSeq:
NP_001101959.2
|
| Others |
UniRef100:
UniRef100_G3V7Q7
UniRef90:
UniRef90_G3V7Q7
UniRef50:
UniRef50_P46940
UniGene:
Rn.106939
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员