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3615 IMPDH2

3615

IMPDH2

inosine monophosphate dehydrogenase 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition inosine monophosphate dehydrogenase 2

研究结论

Date Results Publications
2021-03-20 13:29:00 Genetic variants in the glucocorticoid pathway genes and birth weight. 32886236
2019-11-23 10:50:00 that upregulation of IMPDH2 is a prerequisite for the occurance of aberrant nucleolar function and increased anabolic processes in glioblastoma 31371825
2019-06-15 10:36:00 association of T/C and C/C genotypes in the SNP rs11706052 (IMPDH2) with the occurrence of rejection episodes considering only patients who received immunosuppressive drug mycophenolate mofetil associated with cyclosporine or tacrolimus and corticoids, demonstrated association with a protection against rejection 15.6-fold 30442353
2019-02-16 11:15:00 Study verified that overexpressing IMPDH2 could promote G1/S phase cell cycle transition through activation of PI3K/AKT/mTOR and PI3K/AKT/FOXO1 pathways and facilitate cell invasion, migration and EMT by regulating PI3K/AKT/mTOR pathway. 30518405
2018-09-01 10:31:00 Our study demonstrates IMPDH2 may be served as an independent prognostic biomarker for NPC patients, in which high IMPDH expression suggests poor prognosis of NPC patients. 28389646

名称对应

Type IDs
Synonymous IMPD2, IMPDH-II
Gene
UniProtKB-ID: IMDH2_HUMAN, A0A384N6C2_HUMAN
UniprotKB: P12268, A0A384N6C2
UniParc: UPI000004A47A
EMBL: L33842, L08114, BC006124, BC015567, BC012840, GQ900937, J04208, L39210
Ensembl: ENSG00000178035
KO: hsa:3615
Nucleutide sequences
EMBL-CDS: AAH15567.1, AAH06124.1, AAB70699.1, AAA36113.1, AAA67054.1, AAA36112.1, AAH12840.1, ADO22454.1
Ensembl_TRS: ENST00000326739
Protein sequencees
Ensembl_PRO: ENSP00000321584
RefSeq: NP_000875.2, XP_006713191.1, XP_016861839.1, XP_016861838.1
Others
UniRef100: UniRef100_P12268
UniRef90: UniRef90_P12268
UniRef50: UniRef50_P12268
UniGene: Hs.654400
CCDS: CCDS2786.1

全选

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