| Type | Description |
|---|---|
| Definition | DNA topoisomerase II beta |
| Date | Results | Publications |
|---|---|---|
| 2019-10-26 11:33:00 | Suppression of host DNA-repair pathways that remove TOP2bcc trigger HSV-1 reactivation. Moreover, perturbation of AKT phosphorylation dynamics by downregulating the PHLPP1 phosphatase led to AKT mis-localization and disruption of DSB-induced HSV-1 reactivation. | 30930055 |
| 2014-08-09 11:24:00 | Data indicate that dexrazoxane may protect cardiomyocytes via its catalytic topoisomerase II (TOP2) inhibitory activity. | 24116135 |
| 2012-09-15 11:14:00 | Suggest a role for TopoIIbeta in the repair of N-ethyl N-nitroso urea-mediated strand breaks via base excision repair pathway. | 22433436 |
| 2012-01-14 10:23:00 | TopoIIbeta is an essential component in DSBs repair in primary neurons in both Ku70 and dependent pathways. | 22019940 |
| 2010-10-04 12:58:00 | hnRNP U/SAF-A/SP120 regulates the enzyme DNA Topoisomerase IIbeta in dual ways | 20554522 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
Q14TE9_RAT
UniprotKB:
Q14TE9
UniParc:
UPI0000DA5B67
EMBL:
AB262979
KO:
rno:361100
|
| Nucleutide sequences |
EMBL-CDS:
BAE96971.1
|
| Protein sequencees |
RefSeq:
NP_001094328.1
|
| Others |
UniRef100:
UniRef100_Q14TE9
UniRef90:
UniRef90_Q02880
UniRef50:
UniRef50_P11388
UniGene:
Rn.104585,
Rn.226280
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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