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361100 Top2b

361100

Top2b

DNA topoisomerase II beta

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition DNA topoisomerase II beta

研究结论

Date Results Publications
2019-10-26 11:33:00 Suppression of host DNA-repair pathways that remove TOP2bcc trigger HSV-1 reactivation. Moreover, perturbation of AKT phosphorylation dynamics by downregulating the PHLPP1 phosphatase led to AKT mis-localization and disruption of DSB-induced HSV-1 reactivation. 30930055
2014-08-09 11:24:00 Data indicate that dexrazoxane may protect cardiomyocytes via its catalytic topoisomerase II (TOP2) inhibitory activity. 24116135
2012-09-15 11:14:00 Suggest a role for TopoIIbeta in the repair of N-ethyl N-nitroso urea-mediated strand breaks via base excision repair pathway. 22433436
2012-01-14 10:23:00 TopoIIbeta is an essential component in DSBs repair in primary neurons in both Ku70 and dependent pathways. 22019940
2010-10-04 12:58:00 hnRNP U/SAF-A/SP120 regulates the enzyme DNA Topoisomerase IIbeta in dual ways 20554522

名称对应

Type IDs
Gene
UniProtKB-ID: Q14TE9_RAT
UniprotKB: Q14TE9
UniParc: UPI0000DA5B67
EMBL: AB262979
KO: rno:361100
Nucleutide sequences
EMBL-CDS: BAE96971.1
Protein sequencees
RefSeq: NP_001094328.1
Others
UniRef100: UniRef100_Q14TE9
UniRef90: UniRef90_Q02880
UniRef50: UniRef50_P11388
UniGene: Rn.104585, Rn.226280

全选

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研究热度

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