| Type | Description |
|---|---|
| Definition | integrin linked kinase |
| Date | Results | Publications |
|---|---|---|
| 2021-02-13 13:23:00 | Soft Microenvironments Induce Chemoresistance by Increasing Autophagy Downstream of Integrin-Linked Kinase. | 33008805 |
| 2021-02-06 13:54:00 | ILK silencing inhibits migration and invasion of more invasive glioblastoma cells by downregulating ROCK1 and Fascin-1. | 32506247 |
| 2020-10-06 09:25:00 | Bioinformatics analysis suggested that ILK expression was elevated in ESCC tissues. Further validation indicated that expression of ILK was positively correlated with poor prognosis. Inhibition of ILK kinase activity by specific inhibitor termed Compound 22 (cpd22) blocked ESCC cells proliferation, invasion and migration and attenuated AKT phosphorylation. | 31897228 |
| 2020-08-12 10:50:00 | Drug resistance is closely associated with the inactivation of the hippo pathway protein Merlin/MST/LATS and the activation of YAP. | 31785406 |
| 2020-07-18 10:50:00 | knockdown of ILK in periodontal ligament fibroblasts treated with mechanical stretching altered the composition of small-molecule metabolites | 31630411 |
| Type | IDs |
|---|---|
| Synonymous | HEL-S-28, ILK-1, ILK-2, P59, p59ILK |
| Gene |
UniProtKB-ID:
ILK_HUMAN,
V9HWF0_HUMAN
UniprotKB:
Q13418,
V9HWF0
UniParc:
UPI0000000DC2,
UPI0001914C67,
UPI0001914A99
EMBL:
AC091564,
U40282,
AK293474,
CR749220,
AJ404847,
AK296628,
AF244139,
CH471064,
CR407673,
EU794625,
AJ277481,
BC001554
Ensembl:
ENSG00000166333
KO:
hsa:3611
|
| Nucleutide sequences |
EMBL-CDS:
CAB94832.1,
CAB99253.1,
BAH11516.1,
BAH12404.1,
EAW68688.1,
CAH18077.1,
AAF74449.1,
EAW68689.1,
EAW68690.1,
AAC16892.1,
CAG28601.1,
AAH01554.1,
ACJ13679.1
Ensembl_TRS:
ENST00000420936,
ENST00000528995,
ENST00000396751,
ENST00000299421,
ENST00000532063
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000434492,
ENSP00000299421,
ENSP00000403487,
ENSP00000435323,
ENSP00000379975
RefSeq:
NP_001265371.1,
XP_024304262.1,
XP_024304267.1,
XP_024304263.1,
XP_024304265.1,
XP_024304268.1,
XP_005252962.1,
NP_004508.1,
NP_001014794.1,
XP_011518367.1,
XP_024304266.1,
NP_001014795.1,
XP_016873161.1,
XP_005252961.1,
XP_024304264.1,
NP_001265370.1
|
| Others |
UniRef100:
UniRef100_Q13418
UniRef90:
UniRef90_Q13418
UniRef50:
UniRef50_Q13418
UniGene:
Hs.706355
CCDS:
CCDS7768.1,
CCDS60713.1,
CCDS60712.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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