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360827 Ulk1

360827

Ulk1

unc-51 like autophagy activating kinase 1

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition unc-51 like autophagy activating kinase 1

研究结论

Date Results Publications
2019-12-14 11:45:00 we demonstrate that ULK1 is phosphorylated at Ser317/555/777 and Raptor is also phosphorylated by Phospho-ULK1 (p-ULK1) at these sites are all essential for PEDF-induced mitophagy and reduce the release of mitochondrial and DNA. 30230261
2018-12-22 11:18:00 miR-26a-5p directly acted on the 3'UTR of ULK1 and thus affected the expression of ULK1 29391491
2018-12-22 10:28:00 modulation of Ser758 ULK1 phosphorylation following LRRK2 inhibition is decoupled from the repression of autophagosome biogenesis and independent of mTOR complex 1 activity. 29563162
2018-11-03 10:11:00 The data show that p38 MAPK-ULK1 regulates the levels of both caspase-1 and IL-1beta, supporting the theory that inflammasome itself may be one of the likely targets negatively controlled by autophagy. 29196462
2016-10-29 10:19:00 These results suggest that EA protects against ischemic stroke through the inhibition of autophagosome formation and autophagy, which is mediated through the mTORC1-ULK complex-Beclin1 pathway 26647915

名称对应

Type IDs
Gene
UniProtKB-ID: D3ZMG0_RAT
UniprotKB: D3ZMG0
UniParc: UPI000024FE96
EMBL: CH473973, AC095390
Ensembl: ENSRNOG00000037505
KO: rno:360827
Nucleutide sequences
EMBL-CDS: EDM14029.1
Gene_ORFName: rCG_21843
Ensembl_TRS: ENSRNOT00000056790
Protein sequencees
Ensembl_PRO: ENSRNOP00000053633
RefSeq: XP_006249627.1, NP_001101811.1
Others
UniRef100: UniRef100_D3ZMG0
UniRef90: UniRef90_O70405
UniRef50: UniRef50_O70405
UniGene: Rn.24509

全选

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研究热度

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