| Type | Description |
|---|---|
| Definition | eiger |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:18:00 | Drosophila TNFRs Grindelwald and Wengen bind Eiger with different affinities and promote distinct cellular functions. | 33824334 |
| 2020-12-12 13:23:00 | Upregulated TNF/Eiger signaling mediates stem cell recovery and tissue homeostasis during nutrient resupply in Drosophila testis. | 32669615 |
| 2020-08-01 13:27:00 | such Egr-induced necrosis depends on the catalytic activity of the initiator caspase Dronc and the input from JNK signaling but is independent of their roles in apoptosis. Further mosaic analysis with mutants of scribble (scrib), suggests that Egr/JNK-mediated apoptosis and necrosis establish a two-layered defense system to inhibit the oncogenic growth of scrib mutant cells | 31409797 |
| 2020-02-15 13:06:00 | These results reveal that Tumour Necrosis Factor mediates exposure of phosphatidylserine (PS), which makes tumor cells selectively sensitive to the action of Defensin remotely secreted from tracheal and fat tissues. | 31358113 |
| 2020-01-11 10:41:00 | Activation of Dmp53 in the growth-depleted territory induces the expression of the Eiger, which activates the JNK stress signaling pathway. JNK-dependent expression of the systemic hormone dILP8 reduces the growth and final size of adjacent territories, the production of downstream of JNK and the apoptotic machinery act locally to regulate the proliferation of adjacent epithelial cells. | 31425511 |
| Type | IDs |
|---|---|
| Synonymous | BcDNA:RH51659, CG12919, Dmel\CG12919, Ect1, Egr, Eiger, Regg1, TNF, TNF-alpha, TNFalpha, darth, dt1, regg1 |
| Gene |
UniProtKB-ID:
EIGER_DROME
UniprotKB:
Q8MUJ1
UniParc:
UPI0000083CE6,
UPI00000784D8
EMBL:
AF149799,
BT001838,
BT072996,
AY119233,
AB073865,
AY115551,
AE013599,
AF521176,
BT021371
EnsemblGenome:
FBgn0033483
KO:
dme:Dmel_CG12919
|
| Nucleutide sequences |
EMBL-CDS:
AAM76710.1,
AAM51093.1,
AAX33519.1,
AAO15310.1,
AAM66763.1,
AAS64883.1,
ACO06073.1,
AAN71595.1,
BAC00950.1,
AAF58848.2
Gene_ORFName:
CG12919
EnsemblGenome_TRS:
FBtr0088405,
FBtr0088406
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0087494,
FBpp0087493
RefSeq:
NP_724878.2,
NP_995791.1
|
| Others |
UniRef100:
UniRef100_Q8MUJ1
UniRef90:
UniRef90_Q8MUJ1
UniRef50:
UniRef50_Q8MUJ1
UniGene:
Dm.13536
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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