| Type | Description |
|---|---|
| Definition | solute carrier family 47 member 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-01-04 10:10:00 | Although multiple factors may influence renal handling of drugs, these observations can be accounted for, at least in part, by downregulation of Mate1-mediated apical efflux from tubular cells and Oct2-mediated basolateral uptake. Our results suggest that hyperuricemia could alter the disposition of drugs that are substrates of Mate1 and/or Oct2. | 30951542 |
| 2018-03-10 10:53:00 | mechanism involved in further increasing biliary ADMA levels in sham and I/R groups treated with OCA appears to be MATE-1-dependent | 29346429 |
| 2015-09-26 10:39:00 | Inhibitory effect of atenolol on urinary excretion of metformin via down-regulating MATE1 expression in the kidney of rats | 25486332 |
| 2013-03-09 12:13:00 | renal mRNA level of multidrug and toxin extrusions-1 did not show an age-related increase; the increase in creatinine clearance highly contributed to the age-related increase in urinary creatinine excretion compared to mRNA levels of Oct2 and Mate1 | 23182769 |
| 2010-01-21 00:00:00 | Sp1 functions as basal transcriptional regulator of human and rat MATE1 gene through two GC boxes. May be conserved among species. We have identified rSNP of hMATE1 gene (G-32A) (belonging to Sp1-binding site) that affects promoter activity. | 17855482 |
| Type | IDs |
|---|---|
| Synonymous | MATE1, RGD1311123 |
| Gene |
UniProtKB-ID:
S47A1_RAT
UniprotKB:
Q5I0E9
UniParc:
UPI00004A098F
EMBL:
AB248824,
AB248823,
BC088413
Ensembl:
ENSRNOG00000057404
KO:
rno:360539
|
| Nucleutide sequences |
EMBL-CDS:
BAF02626.1,
AAH88413.1,
BAF02627.1
Ensembl_TRS:
ENSRNOT00000086579
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000074897
RefSeq:
NP_001014140.1,
XP_017452863.1
|
| Others |
UniRef100:
UniRef100_Q5I0E9
UniRef90:
UniRef90_Q5I0E9
UniRef50:
UniRef50_Q5I0E9
UniGene:
Rn.17240
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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