| Type | Description |
|---|---|
| Definition | TNF receptor superfamily member 9 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-20 13:30:00 | 4-1BB Delineates Distinct Activation Status of Exhausted Tumor-Infiltrating CD8(+) T Cells in Hepatocellular Carcinoma. | 31353502 |
| 2020-11-21 13:17:00 | A conserved intratumoral regulatory T cell signature identifies 4-1BB as a pan-cancer target. | 32015231 |
| 2020-06-20 11:20:00 | we report the first genetically well-documented case of EBV-driven T/NK cell lymphoproliferative disorder associated with homozygous mutations in PIK3CD and TNFRSF9, highlighting the potential role of these pathways in the immunity to EBV when EBV infects T cells. | 31537641 |
| 2020-04-04 11:59:00 | the CD137 protein was expressed on pancreatic cancer cell surface, and has identified a novel mechanism by which K-Ras regulates CD137 in pancreatic cancer cells through MAPK and NF-kappaB pathways stimulated by IL-1alpha. | 31288851 |
| 2020-02-29 11:59:00 | To evaluate CAR vulnerability to Tregs, we lymphodepleted mice and transferred CARs alone or with purified Tregs. Cotransfer with Tregs abrogated the efficacy of CD28-4-1BBz CARs, whereas the efficacy of DeltaCD28-4-1BBz CARs remained unperturbed | 30425092 |
| Type | IDs |
|---|---|
| Synonymous | 4-1BB, CD137, CDw137, ILA |
| Gene |
UniProtKB-ID:
TNR9_HUMAN
UniprotKB:
Q07011
UniParc:
UPI00001370F1
EMBL:
U03397,
L12964,
BC006196,
AY438976,
AL009183
Ensembl:
ENSG00000049249
KO:
hsa:3604
|
| Nucleutide sequences |
EMBL-CDS:
AAA53133.1,
AAR05440.1,
AAA62478.2,
AAH06196.1
Ensembl_TRS:
ENST00000615230,
ENST00000377507
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000366729,
ENSP00000478699
RefSeq:
XP_006710681.1,
NP_001552.2
|
| Others |
UniRef100:
UniRef100_Q07011
UniRef90:
UniRef90_Q07011
UniRef50:
UniRef50_Q07011
UniGene:
Hs.86447,
Hs.738942
CCDS:
CCDS92.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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