| Type | Description |
|---|---|
| Definition | BRCA2, DNA repair associated |
| Date | Results | Publications |
|---|---|---|
| 2011-04-30 10:54:00 | Besides BRCA1/2 further high-risk breast cancer genes are known; however they account only for a small fraction of inherited breast cancer cases. Most of them are involved in rare cancer predisposition syndromes. | 20890790 |
| 2010-01-21 00:00:00 | Brca2-/- rats show a phenotype of growth inhibition and sterility in both sexes. Aspermatogenesis in the Brca2-/- rats is due to a failure of homologous chromosome synapsis | 16964288 |
| 2010-01-21 00:00:00 | crystal structure of a COOH terminal BRCA2 domain bound to DSS1; demonstrate that this BRCA2 domain binds single-stranded DNA and show that BRCA2 stimulates RAD51-mediated recombination in vitro | 12228710 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
Q66MH4_RAT
UniprotKB:
Q66MH4
UniParc:
UPI00001D0848
EMBL:
AY691456,
AY691441,
AH014114,
AY691452,
AY691455,
AY691477,
AY691437,
AY691471,
AY691472,
AY691450,
AY691473,
AY691432,
AY691460,
AY691446,
AY691439,
AY691469,
AH014113,
AY691449,
AY691438,
AY691466,
AY691434,
AY691459,
AY691440,
AY691480,
AY691448,
AY691447,
AY691478,
AY691435,
AY691465,
AY691445,
AY691442,
AY691453,
AABR07034923,
AY691479,
AY691463,
AY691470,
AY691462,
AY691444,
AY691454,
AY691451,
AY691481,
AY691483,
AY691475,
AY691443,
AY691436,
AY691482,
AY691461,
AY691467,
AY691468,
AY691464,
AY691474
Ensembl:
ENSRNOG00000001111
KO:
rno:360254
|
| Nucleutide sequences |
EMBL-CDS:
AAU09085.1,
AAU09084.1
Ensembl_TRS:
ENSRNOT00000001475
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000001475
RefSeq:
XP_017453862.1,
XP_017453864.1,
XP_017453865.1,
XP_017453863.1,
NP_113730.2,
XP_017453861.1
|
| Others |
UniRef100:
UniRef100_Q66MH4
UniRef90:
UniRef90_O35923
UniRef50:
UniRef50_P97929
UniGene:
Rn.103225
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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Ensembl: {{protein.nucleotideEnsembl}} |
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Ensembl: {{protein.proteinEnsembl}} |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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