| Type | Description |
|---|---|
| Definition | DNA topoisomerase II alpha |
| Date | Results | Publications |
|---|---|---|
| 2016-09-03 12:13:00 | C-terminal domain of rat topo IIalpha is associated with efficient DNA catenation in vitro, based on comparison of wild-type rat topo IIalpha and its deletion mutants. | 26527691 |
| 2016-02-13 12:37:00 | The genotoxic and antigenotoxic effects of 8 chroman-2,4-diones are reported; the role of their TOPIIalpha inhibitory effect is described. | 26319574 |
| 2014-08-09 11:24:00 | Data indicate that dexrazoxane may protect cardiomyocytes via its catalytic topoisomerase II (TOP2) inhibitory activity. | 24116135 |
| 2013-02-02 11:58:00 | Rac1-regulated mechanisms are required for DNA damage induction and subsequent activation of the DDR following treatment with topo II but not topo I poisons | 23012366 |
| 2010-01-21 00:00:00 | DNA binding activity exists in the head domain | 11995338 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
TOP2A_RAT
UniprotKB:
P41516
UniParc:
UPI0000137197
EMBL:
Z29676,
Z46372,
Z19552
KO:
rno:360243
|
| Nucleutide sequences |
EMBL-CDS:
CAA79611.1,
CAA86496.1
|
| Protein sequencees |
RefSeq:
NP_071519.2
|
| Others |
UniRef100:
UniRef100_P41516
UniRef90:
UniRef90_Q01320
UniRef50:
UniRef50_Q01320
UniGene:
Rn.90996
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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