| Type | Description |
|---|---|
| Definition | Ubiquitin activating enzyme 1 |
| Date | Results | Publications |
|---|---|---|
| 2013-11-16 11:51:00 | Uba1, the E1 enzyme used in ubiquitylation, is required for autophagy and reduction of cell size. | 23873149 |
| 2013-09-07 11:14:00 | These mutants of the E1, the ubiquitin activating enzyme exhibited further reduced lifespan and severe motor impairment. | 23382794 |
| 2012-10-06 11:36:00 | knockdown of SUMO or its E1 and E2 enzymes robustly disrupts proliferating cells in the developing eye, without any detectable effects on the development or differentiation of neighboring post-mitotic cells | 22745316 |
| 2010-01-21 00:00:00 | Data demonstrate that maintaining sufficient E1 function is required both cell autonomously and non-cell autonomously to prevent inappropriate Ras-ERK-dependent growth and proliferation in vivo. | 19366732 |
| 2010-01-21 00:00:00 | This study showed that a reduction in uba1 activity can promote tissue growth in a multicellular organism and raise the possibility that changes in uba1 activity may occur during normal development or in cancer. | 18820468 |
| Type | IDs |
|---|---|
| Synonymous | 2/31, CG1782, DmUba1, Dmel\CG1782, E1, FBtr0088499, UBA-1, Uba 1, l(2)03405, l(2)05642, l(2)s3484, uba-1, uba1 |
| Gene |
UniProtKB-ID:
Q8T0L3_DROME,
A0A0B4KF46_DROME
UniprotKB:
Q8T0L3,
A0A0B4KF46
UniParc:
UPI0000075B94,
UPI000000777B
EMBL:
AY069191,
AE013599
EnsemblGenome:
FBgn0023143
KO:
dme:Dmel_CG1782
|
| Nucleutide sequences |
EMBL-CDS:
AAL39336.1,
AAF58910.2,
AGB93364.1
Gene_ORFName:
CG1782,
Dmel_CG1782,
CG1782,
Dmel_CG1782
EnsemblGenome_TRS:
FBtr0088499,
FBtr0339517
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0087583,
FBpp0308600
RefSeq:
NP_477310.2,
NP_001260831.1
|
| Others |
UniRef100:
UniRef100_Q8T0L3
UniRef90:
UniRef90_Q8T0L3
UniRef50:
UniRef50_Q8T0L3
UniGene:
Dm.5488
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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