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35922 Vang

35922

Vang

Van Gogh

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition Van Gogh

研究结论

Date Results Publications
2020-08-01 14:17:00 Report finds that Vang protein is required for the rotation of the DA1/VA1d dendritic pair. Vang functions in the olfactory receptor neurons (ORNs), suggesting a codependence of ORN axonal and projection neuron (PN) dendritic targeting. Loss of Vang suppressed the repulsion of the VA1d dendrites by Wnt5, indicating that Wnt5 signaling through Vang to direct the rotation of the DA1 and VA1d glomeruli. 32357156
2020-02-29 10:59:00 The authors conclude that Casein Kinase Iepsilon phosphorylation acts as a switch, promoting Strabismus mobility and Dishevelled immobility, thus enhancing sorting of these proteins to opposite cell edges. 31090542
2017-12-02 11:16:00 Vang phosphorylation occurs on conserved N-terminal serine/threonine residues, is mediated by CK1epsilon/Dco, and is critical for polarized membrane localization of Vang and other PCP proteins. 27346358
2017-11-25 15:09:00 The transmembrane proteins Frizzled and Flamingo form a stoichiometric nucleus in the complex, while the relative levels of the other four core proteins can vary independently.we show that robust cell polarization is achieved over a range of complex stoichiometries but is dependent on maintaining appropriate levels of the components Frizzled and Strabismus. 27926869
2014-08-30 10:41:00 Data indicate that Kermit interacts with Go and another PCP component Vang during planar cell polarity (PCP). 24204696

名称对应

Type IDs
Synonymous CG8075, Dmel\CG8075, Stb, Stbm, Vang/Stbm, stb, stbm, stbm/vang, strabismus/Van Gogh, vang, vang/stbm, vangogh/strabismus
Gene
UniProtKB-ID: A1Z7N9_DROME, A0A0B4KEN4_DROME
UniprotKB: A1Z7N9, A0A0B4KEN4
UniParc: UPI000007FE7D, UPI0002946C0E
EMBL: AE013599, BT150320
EnsemblGenome: FBgn0015838
KO: dme:Dmel_CG8075
Nucleutide sequences
EMBL-CDS: AAF58989.1, AGW25602.1, AGB93352.1
Gene_ORFName: Dmel_CG8075, CG8075, CG8075, Dmel_CG8075
EnsemblGenome_TRS: FBtr0088566, FBtr0330624
Protein sequencees
EnsemblGenome_PRO: FBpp0087647, FBpp0303474
RefSeq: NP_477177.1, NP_001260819.1
Others
UniRef100: UniRef100_A0A0B4KEN4
UniRef90: UniRef90_A0A0B4KEN4
UniRef50: UniRef50_A0A0B4KEN4
UniGene: Dm.7726

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