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35878 ana2

35878

ana2

anastral spindle 2

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition anastral spindle 2

研究结论

Date Results Publications
2020-09-19 16:30:00 A molecular mechanism for the procentriole recruitment of Ana2. 31841145
2019-03-23 11:11:00 Plk4 first phosphorylates the extreme N terminus of Ana2, which is critical for subsequent STAN domain modification. Phosphorylation of the central region then breaks the Plk4-Ana2 interaction. This phosphorylation pattern is important for centriole assembly and integrity. 29496738
2018-07-21 10:54:00 Two-step phosphorylation of Ana2 by Plk4 is required for Ana2 recruitment to the centriole. 29263250
2016-03-12 11:41:00 Thus, efficient centriole duplication in flies requires the homo-oligomerisation of both Sas-6 and Ana2. 26002084
2015-02-14 10:49:00 Size exclusion chromatography coupled with multiangle static light scattering demonstrates that LC8 dimers bind Ana2M sites and induce Ana2 tetramerization, yielding an Ana2M4-LC88 complex. 24920673

名称对应

Type IDs
Synonymous Ana-2, Ana2, BcDNA:LD22033, CG8262, Dmel\CG8262, STIL
Gene
UniProtKB-ID: Q9XZ31_DROME, A0A0B4LFU9_DROME
UniprotKB: Q9XZ31, A0A0B4LFU9
UniParc: UPI0000074849, UPI0002B8CE07
EMBL: AF132189, AE013599
EnsemblGenome: FBgn0027513
KO: dme:Dmel_CG8262
Nucleutide sequences
EMBL-CDS: AAD34777.1, AAG22298.1, AHN56014.1
Gene_ORFName: Dmel_CG8262, CG8262, Dmel_CG8262, CG8262
EnsemblGenome_TRS: FBtr0088685, FBtr0339310
Protein sequencees
EnsemblGenome_PRO: FBpp0087766, FBpp0308416
RefSeq: NP_001286216.1, NP_610415.1
Others
UniRef100: UniRef100_Q9XZ31, UniRef100_A0A0B4LFU9
UniRef90: UniRef90_Q9XZ31
UniRef50: UniRef50_Q9XZ31
UniGene: Dm.21568

全选

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研究热度

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