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35862 PGRP-SC2

35862

PGRP-SC2

Peptidoglycan recognition protein SC2

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition Peptidoglycan recognition protein SC2

研究结论

Date Results Publications
2014-04-12 11:43:00 The aging intestine of Drosophila, chronic activation of the transcription factor Foxo reduces expression of peptidoglycan recognition protein SC2 (PGRP-SC2), a negative regulator of IMD/Relish innate immune signaling, and homolog of the anti-inflammatory molecules PGLYRP1-4. 24439372
2010-01-21 00:00:00 Report that PGRP-SC1/2-depleted flies present over-activation of the immune deficiency signaling pathway after bacterial challenge suggesting that these proteins act in the larval gut to prevent activation of this pathway following bacterial ingestion. 16518472

名称对应

Type IDs
Synonymous CG14745, CG14745 PGRP, Dmel\CG14745, PCRP-SC2, PGRP-SC, pgrp-sc, pgrp-sc2
Gene
UniProtKB-ID: PGSC2_DROME
UniprotKB: Q9V4X2
UniParc: UPI0000079E7A
EMBL: AJ556612, AE013599, AJ556621, AJ556620, AJ556622, AJ556613, AJ556618, AJ556619, AJ556616, AJ556614, AJ556617, AJ556615
EnsemblGenome: FBgn0043575
KO: dme:Dmel_CG14745
Nucleutide sequences
EMBL-CDS: CAD89183.1, CAD89186.1, CAD89181.1, CAD89178.1, AAF59051.1, CAD89184.1, CAD89187.1, CAD89180.1, CAD89182.1, CAD89177.1, CAD89179.1, CAD89185.1
Gene_ORFName: CG14745
EnsemblGenome_TRS: FBtr0088709
Protein sequencees
EnsemblGenome_PRO: FBpp0087788
RefSeq: NP_610410.1
Others
UniRef100: UniRef100_Q9V4X2
UniRef90: UniRef90_Q9V4X2
UniRef50: UniRef50_Q9V4X2
UniGene: Dm.23629

全选

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研究热度

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