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35744 Kdm4A

35744

Kdm4A

Lysine (K)-specific demethylase 4A

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition Lysine (K)-specific demethylase 4A

研究结论

Date Results Publications
2019-01-26 11:17:00 the temporal kinetics and pathway utilization during heterochromatic DSB repair depend on dKDM4A-dependent demethylation of heterochromatic histone marks 30578303
2017-09-30 12:10:00 dKDM4A, in addition to its previously characterized role in euchromatin, utilizes both enzymatic and structural mechanisms to regulate heterochromatin organization and functions. 28743002
2016-03-12 10:43:00 Jra recruits the HP1a/KDM4A complex to its gene body region upon osmotic stress to reduce H3K36 methylation levels and disrupt H3K36 methylation-dependent histone deacetylation 25945750
2013-02-23 10:32:00 Appropriate expression levels for some dKDM4A-regulated genes rely on the demethylase activity of dKDM4A, whereas others do not. 23195220
2013-01-05 10:54:00 binding to HP1a is required for dKDM4A-mediated H3K36me3 demethylation at a subset of heterochromatic genes. Collectively, these results show that HP1a functions to target the H3K36 demethylase dKDM4A to heterochromatic genes in Drosophila 22761891

名称对应

Type IDs
Synonymous CG15835, Dmel\CG15835, KDM4A, dJMJD2(1), dKDM4A, dkdm4a
Gene
UniProtKB-ID: KDM4A_DROME, A0A0B4K7U3_DROME
UniprotKB: Q9V333, A0A0B4K7U3
UniParc: UPI000264EC59, UPI000007B405
EMBL: AE013599, AY058636
EnsemblGenome: FBgn0033233
KO: dme:Dmel_CG15835
Nucleutide sequences
EMBL-CDS: AAL13865.1, AAF59172.1, AFH07949.1
Gene_ORFName: CG15835, Dmel_CG15835, CG15835
EnsemblGenome_TRS: FBtr0088886, FBtr0309844
Protein sequencees
EnsemblGenome_PRO: FBpp0087961, FBpp0301578
RefSeq: NP_610331.1, NP_001246194.1
Others
UniRef100: UniRef100_A0A0B4K7U3, UniRef100_Q9V333
UniRef90: UniRef90_Q9V333
UniRef50: UniRef50_Q9V333
UniGene: Dm.4139

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