chk-1 - Serine/threonine-protein kinase chk-1-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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3565921 chk-1

基因描述

Type	Description
Definition	Serine/threonine-protein kinase chk-1

研究结论

Date	Results	Publications
2010-01-21 00:00:00	Chk-1 had an essential role in C. elegans embryo and germline development. More specifically, disruption of chk-1 expression resulted in embryo lethality, which was attributed to a defect in an intrinsic S-M checkpoint.	15326393

名称对应

Type	IDs
Gene	UniProtKB-ID: CHK1_CAEEL UniprotKB: Q9N3Z3 UniParc: UPI00005B2E73, UPI000007C263 EMBL: U44902, BX284605 EnsemblGenome: WBGene00000498 KO: cel:CELE_Y39H10A.7
Nucleutide sequences	EMBL-CDS: AAA93318.1, CCD73288.1, CCD73287.1 Gene_ORFName: Y39H10A.7 EnsemblGenome_TRS: Y39H10A.7a.1, Y39H10A.7b.2, Y39H10A.7b.1
Protein sequencees	EnsemblGenome_PRO: Y39H10A.7a.1, Y39H10A.7b.1, Y39H10A.7b.2 RefSeq: NP_001370816.1, NP_001024234.1
Others	UniRef100: UniRef100_Q9N3Z3 UniRef90: UniRef90_Q9N3Z3 UniRef50: UniRef50_Q9N3Z3 UniGene: Cel.7221

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Pubmed编号	文献信息	发表日期	相关基因
31308550	EPIC: software toolkit for elution profile-based inference of protein complexes. Nat Methods Lucas ZhongMing Hu , Florian Goebels , June H Tan , Eric Wolf , Uros Kuzmanov , Cuihong Wan , Sadhna Phanse , Changjiang Xu , Mike Schertzberg , Andrew G Fraser , Gary D Bader , Andrew Emili	2019-08-01	-
24262006	RAD-6: pyrimidine synthesis and radiation sensitivity in Caenorhabditis elegans. Biochem. J. Alyce Merry , Mengmeng Qiao , Martin Hasler , Patricia E Kuwabara	2014-03-01	-
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
17897480	A global analysis of genetic interactions in Caenorhabditis elegans. J. Biol. Alexandra B Byrne , Matthew T Weirauch , Victoria Wong , Martina Koeva , Scott J Dixon , Joshua M Stuart , Peter J Roy	2007-01-01	mex-3, vps-20, did-2, pop-1, col-48, ftn-2, T20F5.6, unc-73, lin-44, let-502, atp-3, unc-40, cpb-3, lin-35, pnk-1, cdc-25.1, mei-2, cye-1, glh-1, sem-4, lrp-1, ego-1, gld-1, cyc-1, cfim-1, gska-3, sup-17, spd-2, aph-1, ikb-1, sur-6, cco-1, mom-5, fog-3, aph-2, lam-3, hsf-1, par-6, vps-25, gsk-3, F22G12.4, vps-28, pry-1, hmp-2, sur-2, vab-19, ZK546.14, vps-24, mog-5, cpb-2, sma-6, icd-1, vps-32.1, dpy-10, dpy-2, egl-27, B0252.1, tra-2, sod-1, cki-1, mig-5, dab-1, zyg-9, prx-5, let-23, mel-11, kin-15, mex-6, ptp-3, unc-53, unc-130, F54D5.5, lin-29, sop-2, hpr-17, lin-7, mog-4, unc-52, par-2, daf-2, cri-3, clpf-1, npp-9, F59A2.5, C34C12.8, M01F1.8, pitp-1, rpl-37, nhr-6, sel-8, rilp-1, unc-93, C46F11.5, C46F11.4, npr-15, pdi-1, dph-1, alkb-8, C14B1.9
16845399	Systematic mapping of genetic interactions in Caenorhabditis elegans identifies common modifiers of diverse signaling pathways. Nat. Genet. Ben Lehner , Catriona Crombie , Julia Tischler , Angelo Fortunato , Andrew G Fraser	2006-08-01	his-40, egl-30, sop-3, unc-73, let-502, rnt-1, lin-35, gpc-2, swsn-9, pbrm-1, goa-1, ego-1, apr-1, kin-10, unc-120, ceh-6, cdk-8, aph-1, irx-1, sur-6, nhr-49, mom-5, csnk-1, rga-2, gsk-3, pry-1, hmp-2, sur-2, ptr-23, hlh-1, vab-1, tsn-1, fbf-1, fbf-2, rars-2, lin-23, egl-27, cdc-42, lir-1, B0495.2, spv-1, qua-1, jun-1, let-23, ref-1, ptp-3, din-1, trr-1, lin-29, ace-4, unc-52, nhr-80, attf-3, mat-3, swsn-3, nhr-6, mtm-3, cdk-12, ndg-4, mel-28, abi-1, hmg-1.2, algn-1, T26A5.8, ubc-18, lin-37, zfp-1, pat-2, lin-12, glp-1, gei-13, ham-3, pha-1, nob-1, set-16, tpa-1, efn-4, egl-18, ced-10, nstp-6, vab-2, hlh-30, htz-1, eor-1, lag-1, lin-45, nhr-8, F33D4.6, arf-3, hgrs-1, nhr-66, nap-1, pkg-2, F49C12.12, F49C12.11, lin-3, kin-4, let-60, par-5
16549501	Checkpoint silencing during the DNA damage response in Caenorhabditis elegans embryos. J. Cell Biol. Antonia H Holway , Seung-Hwan Kim , Adriana La Volpe , W Matthew Michael	2006-03-27	-
15326393	chk-1 is an essential gene and is required for an S-M checkpoint during early embryogenesis. Cell Cycle Nikolaos Kalogeropoulos , Christina Christoforou , Andrew J Green , Stephen Gill , Neville R Ashcroft	2004-09-01	-
12679813	C. elegans ORFeome version 1.1: experimental verification of the genome annotation and resource for proteome-scale protein expression. Nat. Genet. JÃ©rÃ´me Reboul , Philippe Vaglio , Jean-FranÃ§ois Rual , Philippe Lamesch , Monica Martinez , Christopher M Armstrong , Siming Li , Laurent Jacotot , Nicolas Bertin , Rekin's Janky , Troy Moore , James R Hudson , James L Hartley , Michael A Brasch , Jean Vandenhaute , Simon Boulton , Gregory A Endress , Sarah Jenna , Eric Chevet , Vasilis Papasotiropoulos , Peter P Tolias , Jason Ptacek , Mike Snyder , Raymond Huang , Mark R Chance , Hongmei Lee , Lynn Doucette-Stamm , David E Hill , Marc Vidal	2003-05-01	-
9851916	Genome sequence of the nematode C. elegans: a platform for investigating biology. Science C. elegans Sequencing Consortium	1998-12-11	-

研究热度

该基因近6年没有文献发表

热点单位

排名	科研单位	文献
1	The Wellcome Trust Sanger Institute	1
2	Dana-Farber Cancer Institute and Department of Genetics	1
3	Boston University	1
4	Central China Normal University	1
5	University of Toronto	1

热点人员

排名	研究人员	文献
1	Andrew G Fraser	2
2	C. elegans Sequencing Consortium	1
3	Ben Lehner	1
4	Gregory A Endress	1
5	Lynn Doucette-Stamm	1

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